892869-54-4Relevant articles and documents
Synthesis and biological evaluation of oleanolic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B
Li, Hui,Zou, Hui,Gao, Lixin,Liu, Ting,Yang, Fan,Li, Jingya,Li, Jia,Qiu, Wen-Wei,Tang, Jie
, p. 1117 - 1139 (2012/08/07)
A series of oleanolic acid (OA) derivatives have been synthesized and their inhibitory effects on PTP1B, TCPTP and related PTPs are evaluated. Some compounds with five-membered heterocyclic ring-fused at C-2, C-3 positions showed a dramatic increase in in