117251-95-3Relevant articles and documents
First synthesis of (-)-neplanocin C
Comin, María J.,Rodriguez, Juan B.
, p. 4639 - 4649 (2007/10/03)
(-)-Neplanocin C (4), a minor component of the neplanocin family of antibiotics and a lead drug for the design of several conformationally constrained nucleosides analogues, was enantioselectively synthesized starting from D-ribono-1,4-lactone via a convergent approach in twelve steps. The proton NMR spectrum of 4 was in agreement with the corresponding natural product. Calculated coupling constants obtained from ab initio molecular modeling studies and from previously published X-ray structure of neplanocin C also corresponded to the spectroscopic data. (C) 2000 Elsevier Science Ltd.
CONVENIENT OXIDATIONS OF CARBOHYDRATE DERIVED LACTOLS AND OF ε-HYDROXY-β-KETOPHOSPHONATES
Csuk, Rene,Doerr, Petra
, p. 35 - 44 (2007/10/02)
Convenient oxidation of carbohydrate derived lactols to lactones as well as the oxidation of ε-hydroxy-β-ketophosphonates to their corresponding β,ε-diketophosphonates can be performed with the Dess-Martin periodinane in high yields.
TOTAL SYNTHESIS OF (-)-NEPLANOCIN A
Lim, Mu-ill,Marquez, Victor E.
, p. 5559 - 5562 (2007/10/02)
A total synthesis of (-)-neplanocin A has been accomplished in 15 steps starting from the readily available D-(+)-ribonic acid γ-lactone.