89523-62-6

Basic information

• Product Name: Zinc, chloro(4-chlorophenyl)-
• CAS NO: 89523-62-6
• Molecular Formula: C6H4Cl2Zn
• Molecular Weight: 212.394
• Mol File: 89523-62-6.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Zinc, chloro(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Zinc, chloro(4-chlorophenyl)-(89523-62-6)
• EPA Substance Registry System: Zinc, chloro(4-chlorophenyl)-(89523-62-6)

Safety Data

• Hazardous Substances Data: 89523-62-6(Hazardous Substances Data)

Upstream product

• 7646-85-7 zinc(II) chloride 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 106-39-8 bromochlorobenzene 

Downstream Products

• 37542-28-2 methyl (p-chlorphenyl)glyoxylate 
• 13243-64-6 (R)-3-(4-chlorophenyl)-3-phenylpropanal 
• 2050-68-2 4,4'-dichlorobiphenyl 
• 91335-74-9 1-chloro-4-cyclopentylbenzene 
• 1205517-10-7 1-chloro-4-(2-methylheptyl)benzene 
• 1133204-37-1 2-(4-chlorophenyl)-5-methoxy-3-oxo-3H-indole 1-oxide 
• 1005-33-0 4-chlorophenyldichlorophosphine 

Relevant articles and documents

Enantiomerically Enriched α-Borylzinc Reagents by Nickel-Catalyzed Carbozincation of Vinylboronic Esters

In this paper is described a synthesis of enantiomerically enriched, configurationally stable organozinc reagents by catalytic enantioselective carbozincation of a vinylboronic ester. This process furnishes enantiomerically enriched α-borylzinc intermediates that are shown to undergo stereospecific reactions, producing enantioenriched secondary boronic ester products. The properties of the intermediate α-borylzinc reagent are probed and the synthetic utility of the products is demonstrated by application to the synthesis of (-)-aphanorphine and (-)-enterolactone.

Preparation of Tertiary Amines from Tris(2-cyanoethyl)amine Using Three Successive Cobalt-Catalyzed Electrophilic Aminations with Organozinc Halides

We report a stepwise preparation of triple alkylated or arylated tertiary amines, starting from commercially available tris(2-cyanoethyl)amine using three successive reaction sequences involving a selective oxidation (formation of an N-oxide followed by a

Late Stage Functionalization of Secondary Amines via a Cobalt-Catalyzed Electrophilic Amination of Organozinc Reagents

A general preparation of polyfunctional hydroxylamine benzoates from the corresponding secondary amines is reported. This convenient synthesis allows the setup of a late-stage functionalization of various secondary amines, including pharmaceuticals and peptidic derivatives. Thus, a cross-coupling of hydroxylamine benzoates with various alkyl-, aryl-, and heteroaryl-zinc chlorides in the presence of 5 mol % CoCl2 (25 °C, 2 h) provides a range of polyfunctional tertiary amines. This method was used to prepare penfluridol and gepirone.