89630-82-0

Basic information

• Product Name: 2,5-Furandimethanol, monoacetate
• Synonyms: 2,5-FURANDIMETHANOL, MONOACETATE;acetic acid 5-hydroxymethyl-furan-2-ylmethyl ester;5-acetoxymethylfurfuryl alcohol;2,5-furan-dimethanol monoacetate
• CAS NO: 89630-82-0
• Molecular Formula: C8H10O4
• Molecular Weight: 170.165
• Mol File: 89630-82-0.mol

Chemical Properties

• CAS DataBase Reference: 2,5-Furandimethanol, monoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Furandimethanol, monoacetate(89630-82-0)
• EPA Substance Registry System: 2,5-Furandimethanol, monoacetate(89630-82-0)

Safety Data

• Hazardous Substances Data: 89630-82-0(Hazardous Substances Data)

Upstream product

• 10551-58-3 5-acetoxymethyl-2-furaldehyde 
• 95-51-2 o-chloroaniline 
• 108-42-9 3-chloro-aniline 
• 99-92-3 p-aminobenzophenone 
• 106-40-1 4-bromo-aniline 

Downstream Products

• 1883-75-6 2,5-bis-(hydroxymethyl)furan 

Relevant articles and documents

Reductive amination of 5-acetoxymethylfurfural over Pt/Al2O3 catalyst in a flow reactor

Aminomethylhydroxymethylfuran derivatives are well known for their pharmaceutical activities. In this work, the two-step one-pot procedure for the synthesis of N-substituted 5-(acetoxymethyl)-2-furfuryl amines was proposed, which includes two successive reactions: the condensation of 5-acetoxymethylfurfural (AMF) with primary amines and the reduction of obtained imines with hydrogen over supported metal catalysts in a flow reactor. The comparison of the properties of Au, Pd and Pt catalysts in the hydrogenation of imine obtained by reaction of AMF with aniline showed that Pt-based catalysts (both Pt/Al2O3 and Pt/C) are highly active and provide high selectivity and stability, while Pd and Au nanoparticles supported on γ-alumina and carbon show low selectivity. A wide range of N-substituted 5-(acetoxymethyl)-2-furfuryl amines was synthesized in good to excellent yields using Pt/Al2O3 catalyst and methanol as a solvent.

Flow hydrogenation of 5-acetoxymethylfurfural over Cu-based catalysts

5-Acetoxymethylfurfural (AMF) is a promising starting material for synthesis of the valuable furan derivatives. The catalytic properties of Cu-based catalysts obtained from layered double hydroxides were studied in flow hydrogenation of AMF to 5-(acetoxymethyl)-2-furanmethanol (AMFM) in the present work. The resulting product can be easily converted to 2,5-bis(hydroxymethyl)furan which has significant potential in the production of polymers and pharmaceuticals. It was found that hydrogenation of AMF gives AMFM with selectivity of 98 percent at the full conversion of the substrate under mild reaction conditions (90°C and 10 bar). The influence of the solvent nature, Cu/Al ratio and calcination temperature on the catalyst performance was investigated.