89654-30-8

Usage

Uses

Used in Pharmaceutical Synthesis:
[(2-phenylcyclopropyl)sulfonyl]benzene is used as a reactive intermediate for the synthesis of various pharmaceuticals. Its sulfonyl group, being a strong electron-withdrawing group, contributes to its utility in chemical reactions, making it a crucial component in the development of new drugs.
Used in Agrochemical Synthesis:
Similarly, in the agrochemical industry, [(2-phenylcyclopropyl)sulfonyl]benzene is employed as a key intermediate in the synthesis of different agrochemicals. Its unique structure and properties enable the creation of novel compounds with potential applications in agriculture.
Used in Organic Chemistry Research:
[(2-phenylcyclopropyl)sulfonyl]benzene is also used as a building block in organic chemistry research. Its distinct properties make it an interesting subject for studying various chemical reactions and exploring new synthetic pathways. This contributes to the advancement of knowledge in organic chemistry and the development of innovative chemical processes.

Upstream product

• 96-09-3 styrene oxide 
• 3112-85-4 methylphenylsulfonate 
• 21077-81-6 N,N-(dimethylamino)-methylphenylsulfoxonium tetrafluoroborate 
• 100-52-7 benzaldehyde 
• 16212-06-9 phenyl styryl sulfone 
• 1774-47-6 trimethylsulfoxonium iodide 
• 21297-81-4 C₁₅H₁₅BrO₂S 
• 28187-87-3 (E)-((3-bromoprop-1-en-1-yl)sulfonyl)benzene 
• 960-41-8 (E)-1-phenyl-3-(phenylsulfonyl)prop-2-en-1-one 
• 17494-61-0 ((3-phenylpropyl)sulfonyl)benzene 
• 1228297-54-8 3-chloro-3-phenyl-propyl phenyl sulfone 
• 104-87-0 4-methyl-benzaldehyde 
• 104-88-1 4-chlorobenzaldehyde 
• 123-11-5 4-methoxy-benzaldehyde 

Relevant academic research and scientific papers

Synthesis of substituted tetrahydrofurans via intermolecular reactions of γ-chlorocarbanions of 3-substituted 3-chloro-propylphenyl sulfones with aldehydes

Carbanions of 3-substituted-3-chloropropyl phenyl sulfones add to carbonyl groups of aldehydes to produce aldol type adducts that undergo 1,5-intramolecular substitution giving 2,3,5-trisubstituted tetrahydrofurans. The effect of substituents in the 3-pos

Easy access to trans-2,3-disubstituted cyclobutanones, 2,4,5-trisubstituted 3,6-dihydro-2H-pyrans and cis-substituted phenylcyclopropylsulfones by using the highly versatile 1-phenylsulfenyl- or 1-phenylsulfonyl-cyclopropylketones

The high versatility of 1-phenylsulfenyl- or 1-phenylsulfonyl- cyclopropylketones has been exploited for the regioselective synthesis of trans-2,3-disubstituted cyclobutanones, 2,4,5-trisubstituted 3,6-dihydro-2H-pyrans and cis-2-alkyl- or cis-2-aryl-cycl

Improved dimethylsulfoxonium methylide cyclopropanation procedures, including a tandem oxidation variant

A new procedure for the cyclopropanation of α,β-unsaturated carbonyl compounds and related systems is described which employs trimethylsulfoxonium iodide and an organic base in acetonitile to generate dimethylsulfoxonium methylide in situ; in addition, pr

Reactivity of bifunctional olefins with hydrazine hydrate - Part II

The reaction of 1-aroyl-2-arylsulfonylethenes 1 with different ratios of hydrazine hydrate lead to hydrazones, dimerized products and 2-pyrazolines. The reactivity of pyrazolines has also been studied by dehydrogenation, pyrolysis, nitrosation and acylation.

Phase transfer catalyzed cyclopropanation of trans-styryl aryl sulfones with dimethyl sulfoxonium methylide

Some new trans-aryl cyclopropyl sulfones (II) have been prepared by the cycloaddition of dimethylsulfoxonium methylide to trans-styryl aryl sulfones (I) by two different methods. It is observed that the reaction in presence of a phase transfer catalyst proceeds in a facile manner.

Novel Synthesis of Cyclopropylaminosulfoxonium Salts from (Dimethylamino)phenylsulfoxonium Methylide

The reactions of (dimethylamino)phenylsulfoxonium methylide with aldehydes gave unusual cyclopropylaminosulfoxonium salts in good yields when 1,8-diazabicycloundec-7-ene (DBU) was used as a base.This ylide reacted with aldehydes to give the corresponding betaines, which resulted in the formation of vinylsulfoxonium salts.The additional ylide reacted with these salts to afford cyclopropylsulfoxonium salts.

Convenient One-pot Synthesis of Cyclopropyl Sulfones via Successive Alkylation and Cyclization of Sulfone-stabilized Carbanions

A general one-pot approach to cyclopropyl sulfones has been demonstrated, which involves the alkylation of lithiomethyl phenyl sulfone with an epoxide followed by cyclization of the resulting carbanion.Alkylation of the dianion derived from 3-arylsulfonyl

NOVEL REACTIONS OF AMINOSULFOXONIUM YLIDE WITH EPOXIDES

Reactions of (dimethylamino)phenyloxosulfonium methylide with epoxides were carried out.When aromatic epoxides were used as substrates, cyclopropyl sulfones and oxetanes were obtained.When aliphatic epoxides were used, the products were only the cycloprop