897-18-7

Basic information

• Product Name: 2-(1-NAPHTHYL)-5-PHENYL-1,3,4-OXADIAZOLE
• Synonyms: 2-PHENYL-5-(1-NAPHTHYL)-1,3,4-OXADIAZOLE;2-(1-NAPHTHYL)-5-PHENYL-1,3,4-OXADIAZOLE;ALPHA-NPD;A-NPD;1,3,4-Oxadiazole, 2-(1-naphthalenyl)-5-phenyl-;1,3,4-Oxadiazole, 2-(1-naphthyl)-5-phenyl-;2-(1-NAPHTHYL)-5-PHENYL-1,3,4-OXADIAZOLE 99%;2-(1-Naphthalenyl)-5-phenyl-1,3,4-oxadiazole
• CAS NO: 897-18-7
• Molecular Formula: C₁₈H₁₂N₂O
• Molecular Weight: 272.3
• EINECS: 212-979-3
• Product Categories: Scintillators
• Mol File: 897-18-7.mol
• Article Data: 16

Chemical Properties

• Melting Point: 122-124°C
• Boiling Point: 472.8°C at 760 mmHg
• Flash Point: 241.3°C
• Appearance: /
• Density: 1.219g/cm³
• Vapor Pressure: 1.18E-08mmHg at 25°C
• Refractive Index: 1.652
• CAS DataBase Reference: 2-(1-NAPHTHYL)-5-PHENYL-1,3,4-OXADIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-NAPHTHYL)-5-PHENYL-1,3,4-OXADIAZOLE(897-18-7)
• EPA Substance Registry System: 2-(1-NAPHTHYL)-5-PHENYL-1,3,4-OXADIAZOLE(897-18-7)

Safety Data

• Safety Statements: 22-24/25
• Hazardous Substances Data: 897-18-7(Hazardous Substances Data)

Usage

General Description

2-(1-naphthyl)-5-phenyl-1,3,4-oxadiazole is a chemical compound with a molecular formula C18H12N2O. It is a heterocyclic organic compound that contains an oxadiazole ring. 2-(1-NAPHTHYL)-5-PHENYL-1,3,4-OXADIAZOLE exhibits interesting properties and has potential applications in various fields due to its fluorescent and photo-physical properties. It is commonly used in the field of organic electronics, such as organic light-emitting diodes (OLEDs), as a charge transporting material and in the synthesis of new materials for optoelectronic devices. Additionally, it has been studied for its potential use in medical imaging and as a chemosensor for metal ions. Overall, 2-(1-naphthyl)-5-phenyl-1,3,4-oxadiazole is a versatile compound with potential applications in various industries.

InChI:InChI=1/C18H12N2O/c1-2-8-14(9-3-1)17-19-20-18(21-17)16-12-6-10-13-7-4-5-11-15(13)16/h1-12H

Upstream product

• 879-18-5 naphthalene-1-carbonic acid chloride 
• 825-56-9 2-phenyl-1,3,4-oxadiazole 
• 90-14-2 1-Iodonaphthalene 
• 93-58-3 benzoic acid methyl ester 
• 65-85-0 benzoic acid 
• 26153-26-4 1-naphthylglyoxylic acid 
• 613-94-5 benzoic acid hydrazide 
• 43038-45-5 1-naphthohydrazide 
• 611-73-4 Benzoylformic acid 
• 100-47-0 benzonitrile 
• 67-66-3 chloroform 
• 18039-42-4 5-phenyl-2H-1,2,3,4-tetrazole 
• 591-50-4 iodobenzene 
• 119072-55-8 tert-butylisonitrile 

Relevant articles and documents

Electrochemical Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazoles from α-Keto Acids and Acylhydrazines Under Mild Conditions

1,3,4-Oxadiazoles are a kind of useful heterocycles which can be frequently found in materials and bioactive molecules. In this study, intermolecular electrochemical cyclization between α-keto acids and acylhydrazines has been developed for the synthesis of 2,5-disubstituted 1,3,4-oxadiazoles with the yield up to 91 %. This transformation can be run under mild reaction conditions in the absence of external oxidant, base and transition metal catalyst. Both symmetrical and unsymmetrical 2,5-disubstituted 1,3,4-oxadiazoles could be prepared according to the careful choice of the substrate combination. Gram scale synthesis also illustrates the potential application of this protocol in large preparation.

Iron(III)/TEMPO-Catalyzed Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazoles by Oxidative Cyclization under Mild Conditions

A simple and efficient cationic Fe(III)/TEMPO-catalyzed oxidative cyclization of aroyl hydrazones has been developed for the synthesis of 2,5-disubstituted 1,3,4-oxadiazole derivatives. The reaction offers a broad scope, good functional-group tolerance, and high yields under mild conditions in the presence of O 2.

One-pot cyclization/decarboxylation of α-keto acids and acylhydrazines for the synthesis of 2,5-disubstituted 1,3,4-oxadiazoles under transition-metal-free conditions

A one-pot KI/TBHP-mediated oxidative cyclization of α-keto acids with acylhydrazines was developed. A series of functional 2,5-disubstituted 1,3,4-oxadiazoles were synthesized through a tandem keto amine condensation followed by oxidative cyclization and decarboxylation reactions. This procedure was achieved under transition-metal-free conditions and showed advantages including readily available materials, mild reaction conditions and good group tolerance.