897599-06-3

Upstream product

• 32122-11-5 4-benzyloxy-benzoic acid methyl ester 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 95-14-7 1,2,3-Benzotriazole 
• 1486-51-7 p-(benzyloxy)benzoic acid 
• 1486-50-6 4-(benzyloxy)benzoic acid chloride 

Downstream Products

• 1064179-53-8 1-[4-(benzyloxy)phenyl]-3-{2,4-bis(benzyloxy)-6-(tert-butyldiphenylsilyloxy)-3-[(2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl]phenyl}propane-1,3-dione 
• 1154756-99-6 1-(4-(benzyloxy)phenyl)-3-(4,6-bis(benzyloxy)-2-hydroxy-3-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)phenyl)propane-1,3-dione 
• 95161-87-8 2-[4-(benzyloxy)phenyl]-4H-chromen-4-one 
• 4143-63-9 4'-hydroxyflavone 
• 14919-49-4 3-hydroxy-2-(4-hydroxy-phenyl)-chromen-4-one 
• 102468-65-5 2-(4-(benzyloxy)phenyl)-3-hydroxy-4H-chromen-4-one 

Relevant academic research and scientific papers

Synthetic studies of fisetin, myricetin and nobiletin analogs and related probe molecules

We synthesized a series of analogs of fisetin, myricetin and nobiletin, as well as related fluorescein- and biotin-based flavone-probe molecules, on a suitable scale for biological and structure-activity relationship studies.

Concise synthesis of chafurosides A and B

The regioselective synthesis of chafurosides A (1) and B (2) from the same methyl ketone 5 was accomplished using a novel protecting group strategy. Both flavone rings were constructed from β-diketone intermediate 4, which was readily obtained by condensation of an acyl donor and ketone 5. Construction of the dihydrofuran ring was achieved via an intramolecular Mitsunobu reaction.