897961-42-1

Basic information

• Product Name: (2''S)-1-[2-(3-benzyloxy-2-triethylsilanyloxypropyl)-[1,3]-dithian-2-yl]-5-triethylsilanyloxy-8-trimethylsilanyl-oct-7-yn-2-one
• Synonyms: (2''S)-1-[2-(3-benzyloxy-2-triethylsilanyloxypropyl)-[1,3]-dithian-2-yl]-5-triethylsilanyloxy-8-trimethylsilanyl-oct-7-yn-2-one
• CAS NO: 897961-42-1
• Molecular Weight: 723.317
• Mol File: 897961-42-1.mol

Chemical Properties

• CAS DataBase Reference: (2''S)-1-[2-(3-benzyloxy-2-triethylsilanyloxypropyl)-[1,3]-dithian-2-yl]-5-triethylsilanyloxy-8-trimethylsilanyl-oct-7-yn-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2''S)-1-[2-(3-benzyloxy-2-triethylsilanyloxypropyl)-[1,3]-dithian-2-yl]-5-triethylsilanyloxy-8-trimethylsilanyl-oct-7-yn-2-one(897961-42-1)
• EPA Substance Registry System: (2''S)-1-[2-(3-benzyloxy-2-triethylsilanyloxypropyl)-[1,3]-dithian-2-yl]-5-triethylsilanyloxy-8-trimethylsilanyl-oct-7-yn-2-one(897961-42-1)

Safety Data

• Hazardous Substances Data: 897961-42-1(Hazardous Substances Data)

Upstream product

• 109-80-8 1.3-propanedithiol 
• 897961-41-0 (2S)-1-benzyloxy-2,9-bistriethylsilanyloxy-12-trimethylsilanyldodeca-4,11-diyn-6-one 
• 897961-94-3 (1S)-(1-benzyloxymethyl-but-3-ynyloxy)-triethyl-silane 
• 897961-25-0 (5S)-6-benzyloxy-5-triethylsilanyloxy-hex-2-ynal 
• 100-39-0 benzyl bromide 
• 2930-05-4 (S)-benzyl glycidyl ether 
• 124662-61-9 (S)-5-Benzyloxy-4-hydroxy-1-pentyne 
• 484664-27-9 (2S)-1-benzyloxy-5-trimethylsilanyl-pent-4-yn-2-ol 
• 897961-40-9 (2S)-1-benzyloxy-9-hydroxy-2-triethylsilanyloxy-12-trimethylsilanyldodeca-4,11-diyn-6-one 
• 897961-39-6 (7S)-8-benzyloxy-1-oxiranyl-7-triethylsilanyloxyoct-4-yn-3-one 
• 897961-35-2 (9S)-10-benzyloxy-9-triethylsilanyloxydec-1-en-6-yn-5-one 
• 897961-88-5 (9S)-10-benzyloxy-9-triethylsilanyloxydec-1-en-6-yn-5-ol 

Relevant articles and documents

Chemical variation of natural product-like scaffolds: Design and synthesis of spiroketal derivatives

The design and synthesis of spiroketal structures and their chemical modification, leading to a collection of new small molecules for biological evaluation as orally-bioavailable lead compounds is described. Both [6,5]- and [6,6]-membered ring spiroketal units have been prepared in a stereochemically-varying fashion starting from commercially available (R)- or (S)-glycidol, in ten, eleven and twelve linear steps, in overall yields of 45, 40 and 20%, respectively. Further elaboration according to Lipinski's guidelines has given a collection of structurally-diverse, new spiroketal derivatives in high yields and with high purity. The Royal Society of Chemistry 2006.