89868-06-4

Basic information

• Product Name: 4-AMINO-6-PHENYL-3(2H)-PYRIDAZINONE
• Synonyms: 4-AMINO-6-PHENYL-3(2H)-PYRIDAZINONE;4-Amino-6-phenyl-2H-pyridazin-3-one;3(2H)-Pyridazinone,4-aMino-6-phenyl-;4-amino-6-phenylpyridazin-3(2H)-one
• CAS NO: 89868-06-4
• Molecular Formula: C₁₀H₉N₃O
• Molecular Weight: 187.2
• Mol File: 89868-06-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Density: 1.337g/cm³
• Refractive Index: 1.672
• CAS DataBase Reference: 4-AMINO-6-PHENYL-3(2H)-PYRIDAZINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-6-PHENYL-3(2H)-PYRIDAZINONE(89868-06-4)
• EPA Substance Registry System: 4-AMINO-6-PHENYL-3(2H)-PYRIDAZINONE(89868-06-4)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 89868-06-4(Hazardous Substances Data)

Usage

General Description

4-AMINO-6-PHENYL-3(2H)-PYRIDAZINONE is a chemical compound with the molecular formula C11H9N3O. It belongs to the class of pyridazinones and is characterized by a pyridazinone core with an amino group at the fourth position and a phenyl group at the sixth position. 4-AMINO-6-PHENYL-3(2H)-PYRIDAZINONE has potential applications in pharmaceutical and research fields due to its unique chemical structure and properties. It may be used in the synthesis of various organic compounds and could have potential biological activities that make it of interest to medicinal chemists and pharmaceutical researchers. However, further research and testing are needed to fully explore its potential applications and properties.

InChI:InChI=1/C10H9N3O/c11-8-6-9(12-13-10(8)14)7-4-2-1-3-5-7/h1-6H,(H2,11,12)(H,13,14)

Upstream product

• 2166-31-6 6-phenylpyridazin-3(2H)-one 
• 34753-27-0 ethyl 2,3-dihydro-3-oxo-6-phenyl-4-pyridazinecarboxylate 
• 64942-62-7 3,4-dichloro-6-phenylpyridazine 
• 98-86-2 acetophenone 
• 298-12-4 Glyoxilic acid 
• 221196-01-6 3-chloro-6-phenyl-pyridazin-4-ylamine 
• 87769-56-0 2,3-dihydro-3-oxo-6-phenyl-4-pyridazinecarboxamide 

Downstream Products

• 518344-25-7 4,5-diamino-6-phenyl-2H-pyridazin-3-one 
• 881993-34-6 C₂₅H₃₂BrN₃O₇ 
• 350578-58-4 C₂₀H₂₄N₆O₅ 
• 350578-59-5 C₂₀H₂₆N₄O₅ 
• 350578-56-2 C₂₀H₂₄BrN₃O₅ 
• 350578-61-9 (5-amino-6-phenyl-pyridazin-4-yl)-phosphoramidic acid diethyl ester 

Relevant articles and documents

SUBSTITUTED TRICYCLICS AND METHOD OF USE

The present invention provides for compounds of formula (I) wherein X, Y, and R1 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions mediated and modulated by CFTR, including cystic fibrosis, Sj?gren's syndrome, pancreatic insufficiency, chronic obstructive lung disease, and chronic obstructive airway disease. Also provided are pharmaceutical compositions comprised of one or more compounds of formula (I).

Pyrazino-pyridazine derivatives as ligands for gaba receptors

A class of pyrazino[2,3-d]pyridazine derivatives, possessing an optionally substituted cycloalkyl, phenyl or heteroaryl substituent at the 5-position, a substituted alkoxy moiety at the 3-position, and a range of substituents at the 2-position, are selective ligands for GABAA receptors, in particular having high affinity for the α2 and/or α3 and/or α5 subunit thereof, and are accordingly of benefit in the treatment and/or prevention of adverse conditions of the central nervous system, including anxiety, ceonvulsions and cognitive disorders.

Synthesis of 4-amino-6-phenyl-3(2H)-pyridazinones: A general procedure

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