89996-01-0Relevant academic research and scientific papers
Development of a mitochondrial-targeted two-photon fluorescence turn-on probe for formaldehyde and its bio-imaging applications in living cells and tissues
Xu, An,Tang, Yonghe,Lin, Weiying
, p. 8325 - 8329 (2018)
A mitochondrial-targeted two-photon fluorescent formaldehyde probe (MT-FA) with a large emission enhancement was developed. MT-FA could image formaldehyde in the mitochondria of living cells for the first time, and also could image formaldehyde in living liver tissue slices.
COUNTERCURRENT RARE EARTH SEPARATION PROCESS
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Paragraph 0178; 0192, (2021/09/17)
A method for extracting a rare earth metal from a mixture of one or more rare earth metals, said method comprising countercurrently contacting an acidic solution of the rare earth metal with a composition which comprises an ionic liquid to form an aqueous phase and a non-aqueous phase into which the rare earth metal has been selectively extracted.
Live-Cell Localization Microscopy with a Fluorogenic and Self-Blinking Tetrazine Probe
Werther, Philipp,Yserentant, Klaus,Braun, Felix,Kaltwasser, Nicolai,Popp, Christoph,Baalmann, Mathis,Herten, Dirk-Peter,Wombacher, Richard
supporting information, p. 804 - 810 (2019/11/26)
Recent developments in fluorescence microscopy call for novel small-molecule-based labels with multiple functionalities to satisfy different experimental requirements. A current limitation in the advancement of live-cell single-molecule localization micro
ENHANCED SEPARATION OF RARE EARTH METALS
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Page/Page column 32, (2020/01/08)
A method for extracting a rare earth metal from a mixture of one or more rare earth metals, said method comprising contacting an acidic solution of the rare earth metal with a composition which comprises an ionic liquid to form an aqueous phase and a non-aqueous phase into which the rare earth metal has been selectively extracted, wherein the ionic liquid has the formula [Cat+][X'], where [Χ'] represents a phosphinate anion.
IONIC LIQUID PREPARATION
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Page/Page column 30; 36, (2020/01/08)
A process for preparing a cationic species [Cat + ] for an ionic liquid, said process comprising reacting a reagent (1) H 2 N-L -[Z] with a reagent (2) LG-L 2 -EDG, to form a cationic species EDG-L 2 -[Z + ]-L -N(L 2 -EDG) 2, wherein the process is carried out in a sealed reactor at a temperature of at least 100 °C.
Small molecule probe as well as preparation method and application thereof (by machine translation)
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Paragraph 0035-0038, (2020/01/12)
The invention discloses a photocontrol targeted mitochondria-containing small-molecule probe and a preparation method thereof, and a preparation method of, the micromolecule probe containing the mitochondria-located mitochondria, through an orthogonal, re
Fluorescent probe for detecting formaldehyde-targeted mitochondria as well as preparation method and application thereof
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Paragraph 0018, (2018/07/30)
The invention provides a fluorescent probe Na-FA-Mito. The fluorescent probe has the advantages that the reaction is sensitive, the detection limit is low, and the specificity is good; the fluorescentprobe can be used for detecting formaldehyde-targeted mitochondria. The chemical name of the fluorescent probe is brominated N-(2-formamido ethyl-N-(3-triphenyl phosphine propyl))-4-hydrazino-1,8-naphthalimide salt. The fluorescent probe is used for detecting the formaldehyde in solutions or cells.
P-nitrophenoxy betulin (28) formyl ester and betulin derivatives synthesized therefrom, and preparation method and application thereof
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Paragraph 0074; 0076; 0078, (2018/04/21)
The invention discloses p-nitrophenoxy betulin (28) formyl ester and betulin derivatives synthesized therefrom, and a preparation method and an application thereof, and belongs to the technical fieldof pharmaceutical chemical. Four derivatives are synthes
Design, Synthesis, and Characterization of Brequinar Conjugates as Probes to Study DHODH Inhibition
Madak, Joseph T.,Cuthbertson, Christine R.,Chen, Wenmin,Showalter, Hollis D.,Neamati, Nouri
supporting information, p. 13875 - 13878 (2017/09/18)
Brequinar, a potent dihydroorotate dehydrogenase (DHODH) inhibitor, has been evaluated in multiple clinical trials as a potential treatment for cancer. To further understand brequinar-based DHODH inhibition and DHODH′s therapeutic relevance in cancer, we
Hydrogen sulfide molecule fluorescent probe with mitochondrial targeting and two-photon property as well as preparation method and application of hydrogen sulfide molecule fluorescent probe
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Paragraph 0038; 0039; 0040, (2017/04/12)
The invention discloses a hydrogen sulfide molecule fluorescent probe with mitochondrial targeting and a two-photon property as well as a preparation method and application of the hydrogen sulfide molecule fluorescent probe, and belongs to the technical field of analytical chemistry. A molecular formula of the probe is C35H29N5O3PBr, and a structural formula of the probe is shown in a formula I (shown in the description). The hydrogen sulfide molecule fluorescent probe prepared by the preparation method disclosed by the invention is simple in preparation and matured in synthetic route, can be used for quickly and accurately detecting hydrogen sulfide of mitochondria in cells, can perform fluorescence imaging, and is applied to sensing detection of hydrogen sulfide in a water environment and a biological cell system. Besides, the probe has the characteristics of good selectivity, high response speed, high capability of resisting jamming of other molecules, and the like.
