90-45-9Relevant articles and documents
Synthesis and performance research of selenazole fluorescent dye compound
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Paragraph 0007; 0017, (2020/02/27)
The invention discloses synthesis and performance research of a selenazole fluorescent dye compound; benzoselenazole is used as a recognition group for detecting the HOCl level in cells, and a reliable method is provided for detecting the HOCl level in a biological system in real time. A probe disclosed by the invention has the technical effects that the probe can sensitively and selectively respond to HOCl and detect the HOCl level in tumor living cells, so that the HOCl level in the tumor living cells can be rapidly monitored, and a new method can be provided for early detection of tumors. Compared with other fluorescent compounds, the fluorescent reaction system containing the selenide functional group is simple, has the characteristics of high luminous efficiency, small background interference and the like, and is a fluorescent probe with a wide prospect.
9-Substituted acridines as effective corrosion inhibitors for mild steel: Electrochemical, surface morphology, and computational studies
Li, Hui-Jing,Liu, Ying,Wang, Li-Juan,Wu, Yan-Chao,Zhang, Weiwei,Zhang, Yinlin
, p. 6464 - 6474 (2020/05/13)
Three 9-substituted acridines, namely 9-carboxyacridine (CA), 9-methylacridine (MA), and 9-aminoacridine (AA), were designed and synthesized for the development of effective inhibitors for mild steel corrosion in a 15% HCl solution. The corrosion-resistance ability was tested by weight-loss tests, electrochemical techniques, surface-topography analyses (SEM, SECM, and XPS), and contact angle measurements. The results indicated the inhibition performance followed the order of η(AA) > η(MA) > η(CA), and these acridines acted as mixed type inhibitors with a predominant restrained cathode process. The adsorption of the three acridines on a mild steel surface obeyed the Langmuir adsorption isotherm and involved both physisorption and chemisorption modes. Surface analysis and characterization confirmed the existence of an adsorbed film. Quantum chemical calculations were performed to provide mechanistic insights into the roles of the different substituents (-COOH, -CH3, and -NH2) on the corrosion-inhibition behavior of the three acridines. Molecular dynamics (MD) simulations were carried out to explore the configurational adsorption behavior of these 9-substituted acridines on the Fe(110) surface.
Imine acridine derivative fluorescent probe as well as preparation method and application thereof in detection of MORAb-3-1 antibodies
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Paragraph 0022; 0023; 0024, (2018/11/22)
The invention discloses an imine acridine derivative fluorescent probe as well as a preparation method and application thereof in detection of MORAb-3-1 antibodies. A detection method of the MORAb-3-1antibody is established by combining specificities of antigens and antibodies. The detection method of the MORAb-3-1 antibody has the technical effects that 1, an imine acridine derivative biologicalprobe is combined with HSA (human serum albumin), and then combined with the MORAb-3-1 antibody for the first time, and the MORAb-3-1 antibody is observed under a fluorescent inverted microscope; 2,the combination of the probe and the antigen is judged by utilizing the photophysical and photochemistry natures; 3, the sensitivity is high, the operation is simple, convenient and rapid, and the accuracy is realized; compared with the traditional dye method, the advantages are more excellent. The formula is shown in the description.
