900504-52-1Relevant academic research and scientific papers
Total synthesis of dictyodendrins B and E, and formal synthesis of dictyodendrin C
Tao, Pengyu,Liang, Jingjing,Jia, Yanxing
, p. 5735 - 5748 (2014/11/07)
A full account of the concise total syntheses of dictyodendrins B and E, and the formal synthesis of dictyodendrin C are described. A palladium-catalysed Larock indole synthesis was used to form the highly substituted indole core, and a palladium-mediated
Total synthesis of dictyodendrins A-E
Tokuyama, Hidetoshi,Okano, Kentaro,Fujiwara, Hideto,Noji, Toshiharu,Fukuyama, Tohru
, p. 560 - 572 (2011/10/03)
A highly efficient total synthesis of dictyodendrins A-E was accomplished. The synthesis features a novel benzyne-mediated one-pot indoline formation/cross-coupling sequence for the construction of a highly substituted key indoline intermediate. Peripheral substituents were introduced onto this intermediate in a modular fashion to complete the total synthesis of dictyodendrins A-E. A benzyne-mediated one-pot indoline formation/cross-coupling sequence is used for the construction of a highly substituted common indole intermediate. The peripheral substituents were introduced using a Friedel-Crafts reaction on the indole intermediate in a modular fashion to complete the total synthesis. Copyright
