90074-16-1

Upstream product

• 131829-44-2 (2R,3S)-3-ethyl-2-methyl-oxirane-2-carbaldehyde 
• 123-11-5 4-methoxy-benzaldehyde 
• 16958-19-3 (2E)-2-methyl-2-penten-1-ol 
• 76639-80-0 ((2S,3S)-3-ethyl-2-methyloxiran-2-yl)methanol 
• 134744-44-8 (2R,4S,5R)-5-Ethyl-2-(4-methoxy-phenyl)-4-methyl-4-vinyl-[1,3]dioxolane 
• 96016-44-3 (2S,3R)-2,3-<(R)-(4-methoxybenzylidene)dioxy>-2-methylpentanol 
• 1515-81-7 1-methoxy-4-(methoxymethyl)benzene 
• 64638-73-9 4,5-didesoxy-2-C-methyl-2-O-benzyl-3-O-formyl-D-erythro-al-pentose 
• 134744-42-6 Benzoic acid 2-[(2R,4R,5S)-2-(4-methoxy-phenyl)-5-methyl-5-vinyl-[1,3]dioxolan-4-yl]-ethyl ester 
• 134744-32-4 (1R,2S,3R,5R)-2-Allyloxy-3-benzyloxymethoxy-6,8-dioxa-bicyclo[3.2.1]octane 
• 134744-34-6 (1R,3R,5R)-3-Benzyloxymethoxy-6,8-dioxa-bicyclo[3.2.1]octan-2-one 
• 134776-79-7 Benzoic acid 2-((4R,5S)-2,2,5-trimethyl-5-vinyl-[1,3]dioxolan-4-yl)-ethyl ester 
• 134744-43-7 (2R,4S,5R)-5-(2-Bromo-ethyl)-2-(4-methoxy-phenyl)-4-methyl-4-vinyl-[1,3]dioxolane 
• 134744-33-5 (1R,2S,3R,5R)-3-Benzyloxymethoxy-6,8-dioxa-bicyclo[3.2.1]octan-2-ol 

Downstream Products

• 133782-39-5 (1R,2R,4R,6R)-6-Benzyloxy-1-[(2R,4S,5R)-5-ethyl-2-(4-methoxy-phenyl)-4-methyl-[1,3]dioxolan-4-yl]-1-hydroxy-2,4-dimethyl-6-[(4R,5S,6R)-2,2,5-trimethyl-6-((S)-1-methyl-allyl)-[1,3]dioxan-4-yl]-heptan-3-one 
• 133814-77-4 (1S,2S,4R,6R)-6-Benzyloxy-1-[(2R,4S,5R)-5-ethyl-2-(4-methoxy-phenyl)-4-methyl-[1,3]dioxolan-4-yl]-1-hydroxy-2,4-dimethyl-6-[(4R,5S,6R)-2,2,5-trimethyl-6-((S)-1-methyl-allyl)-[1,3]dioxan-4-yl]-heptan-3-one 
• 90094-00-1 (2R,3S,4S,6R,8E,10S,11R)-3-tert-butyldimethylsilyloxy-10,11-<(R)-(4-methoxybenzylidene)dioxy>-2,4,6,10-tetramethyl-7-oxo-8-tridecenoic acid 
• 133782-49-7 C₄₃H₆₄O₈ 
• 133782-49-7 C₄₃H₆₄O₈ 
• 133814-81-0 (1S,2R,3R,4R,6R)-6-Benzyloxy-1-[(2R,4S,5R)-5-ethyl-2-(4-methoxy-phenyl)-4-methyl-[1,3]dioxolan-4-yl]-2,4-dimethyl-6-[(4R,5S,6R)-2,2,5-trimethyl-6-((S)-1-methyl-allyl)-[1,3]dioxan-4-yl]-heptane-1,3-diol 
• 133782-48-6 (1R,2S,3S,4R,6R)-6-Benzyloxy-1-[(2R,4S,5R)-5-ethyl-2-(4-methoxy-phenyl)-4-methyl-[1,3]dioxolan-4-yl]-2,4-dimethyl-6-[(4R,5S,6R)-2,2,5-trimethyl-6-((S)-1-methyl-allyl)-[1,3]dioxan-4-yl]-heptane-1,3-diol 
• 133782-48-6 (1R,2S,3R,4R,6R)-6-Benzyloxy-1-[(2R,4S,5R)-5-ethyl-2-(4-methoxy-phenyl)-4-methyl-[1,3]dioxolan-4-yl]-2,4-dimethyl-6-[(4R,5S,6R)-2,2,5-trimethyl-6-((S)-1-methyl-allyl)-[1,3]dioxan-4-yl]-heptane-1,3-diol 
• 133782-40-8 Benzoic acid (S)-2-[(4R,5S,6R)-6-((1R,3R)-3-{(4S,5S,6R)-6-[(1S,2R)-2-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-1-methyl-butyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-1-hydroxy-1-methyl-butyl)-2,2,5-trimethyl-[1,3]dioxan-4-yl]-propyl ester 

Relevant academic research and scientific papers

Short Enantioselective Approach to a Building Block for Macrolide Syntheses

The protected α,β-dihydroxy aldehyde 2, a key building block for several macrolide antibiotics, has been synthesized from the epoxy alcohol 6.Oxidation furnishes the corresponding aldehyde 7, which is acetalized with ketones in the presence of SnCl4, with

Stereocontrolled synthesis of erythronolides A and B in a (C5-C9) + (C3-C4) + (C1-C2) + (C11-C13) sequence from 1,6-anhydro-β-D-glycopyranose (levoglucosan). Part 1. Synthesis of C1-C10 and C11-C13 segments

An approach to the synthesis of aglycones of macrolide antibiotics erythromycin A and B is discussed and preparation of common C1-C10 and C11-C13 segments starting from levoglucosane is described.

HIGHLY STEREOSELECTIVE SYNTHESIS OF METHYNOLIDE, THE AGLYCONE OF THE 12-MEMBERED RING MACROLIDE METHYMYCIN, FROM D-GLUCOSE

A highly stereoselective and efficient synthesis of methynolide, the aglycone of 12-membered macrolide methymycin, was achieved from of C1-C8 and C9-C13 segments synthesized from D-glucose by employing some stereoselective reactions and benzyl-type protec