901113-90-4

Upstream product

• 934-34-9 2(3H)-Benzothiazolone 
• 133044-31-2 6-benzoyl-2(3H)-benzothiazolone 
• 65-85-0 benzoic acid 
• 912266-39-8 5-benzoyl-2-aminothiophenol 
• 105-36-2 ethyl bromoacetate 
• 5325-20-2 2H-1,4-benzothiazin-3-one 
• 98-88-4 benzoyl chloride 

Downstream Products

• 901114-02-1 ethyl 3-[4-(2-{7-[(hydroxyimino)(phenyl)methyl]-3-oxo-2,3-dihydro-4H-1,4-benzothiazin-4-yl}ethoxy)phenyl]-2-(2,2,2-trifluoroethoxy)propanoate 
• 901114-04-3 3-[4-(2-{7-[(hydroxyimino)(phenyl)methyl]-3-oxo-2,3-dihydro-4H-1,4-benzothiazin-4-yl}ethoxy)phenyl]-2-(2,2,2-trifluoroethoxy)propanoic acid 
• 901114-01-0 ethyl 2-ethoxy-3-[4-(2-{7-[(hydroxyimino)(phenyl)methyl]-3-oxo-2,3-dihydro-4H-1,4-benzothiazin-4-yl}ethoxy)phenyl]propanoate 
• 901113-94-8 2-ethoxy-3-[4-(2-{7-[(hydroxyimino)(phenyl)methyl]-3-oxo-2,3-dihydro-4H-1,4-benzothiazin-4-yl}ethoxy)phenyl]propanoic acid 
• 901114-06-5 7-{[(E)-methoxyimino]phenylmethyl}-4H-benzo[1,4]thiazin-3-one 

Relevant academic research and scientific papers

Heterocyclic Oxime Compounds, A Process For Their Preparation And Pharmaceutical Compositions Containing Them.

Compounds of formula (I): wherein: X represents an oxygen atom or a sulphur atom,R1, R2, R3 and R4 are as defined in the description,A represents an alkylene chain as defined in the description, andB represents

Aromatase inhibitor compounds and uses thereof

The invention concerns the use of a compound of formula (I) inhibitor of aromatase for the preparation of a pharmaceutical formulation intended for treatment of cancer or psoriasis. It equally relates to compounds of formula (I), notably for their use as active ingredients of a medication.

Synthesis of 6- and 7-acyl-4H-benzothiazin-3-ones

Synthesis of 6- and 7-substituted benzoxazin-3-ones was already described in the literature by acylation of the corresponding benzoxazin-3-ones or cyclization of the corresponding 4- or 5-acyl-2-aminophenols. This paper describes original synthetic pathwa