90197-99-2Relevant academic research and scientific papers
Dimethyl N,N′-oxalamidodiethanoate
Armelin, Elaine,Urpi, Lourdes,Solans, Xavier,Puiggali, Jordi
, p. 932 - 933 (2001)
The title compound, dimethyl 2,2′-(oxalyldiimino)diethanoate, C8H12N2O6, exhibits a network of hydrogen bonds between amide and ester groups. Molecules lie on inversion centres and show a planar conformation for both the oxalamide and ester groups. The glycine residues adopt a conformation close to the polyglycine II structure.
Synthesis of oxalic acid derivatives and their antitumor activity in experiments in vivo
Fedorov,Goncharova,Rajevskaya,Eremeev,Utenyshev,Fadeev,Bogdanov,Konovalova,Aldoshin
, p. 694 - 699 (2018)
A series of amino acid derivatives of oxalic acid were obtained. In combination therapy with conventional cytostatics used in lower doses, the new compounds substantially increase the efficacy of the drugs in the treatment of experimental P388 murine leukemia and some its drug-resistant strains.
Oxalopeptides as Core Motifs for Protein Design
Ranganathan, Darshan,Vaish, Narendra K.,Shah, Kavita,Roy, Raja,Madhusudanan, K. P.
, p. 92 - 94 (2007/10/02)
Oxalopeptides are demonstrated to be useful core motifs for bi-directional chain elongation leading to peptide homologues with interesting folding behaviour, thus constituting a useful strategy for protein backbone modification.
UNE NOUVELLE METHODE DE SYNTHESE PEPTIDIQUE INTRAMOLECULAIRE, APPLICABLE A LA SARCOSINE, A L'AIDE DE DERIVES DE L'ACIDE OXALIQUE
Mulliez, Michel,Royer, Jacques
, p. 5143 - 5152 (2007/10/02)
Two steps are postulated in a new method of intramolecular peptide synthesis using oxalic acid derivates (Fig. 1).Both are verified with model derivatives incorporating one sarcosine residue: cyclisation of 2d into 5 (Fig. 4) and aminolysis of 5 leading t
MACROHETEROCYCLES. 12. SYNTHESIS AND PROPERTIES OF MACROCYCLIC TETRAAMIDES
Luk'yanenko, N. G.,Bogat-skii, A. V.,Popkov, Yu. A.
, p. 847 - 852 (2007/10/02)
The N,N'-bis(methoxycarbonylmethyl)diamides of the corresponding acids were obtained by the reaction of glycine methyl ester hydrochloride with oxalic, succinic, adipic, diglycolic, and triglycolic acid dichlorides.Fourteen new macrocyclic tetraamides were obtained by the reaction of these diamides with various diamines.The structures of the synthesized compounds were proved by means of their IR, PMR, and mass spectra.
