90246-43-8

Upstream product

• 75-16-1 methylmagnesium bromide 
• 90246-42-7 (S)-5-(benzyloxy)-1-(trimethylsilyl)-1-pentyn-3-yl acetate 
• 90246-41-6 (S)-5-(benzyloxy)-1-(trimethylsilyl)-1-pentyn-3-yl benzoate 
• 75-77-4 chloro-trimethyl-silane 
• 1026838-38-9 (R)-1-benzyloxy-5,5-dibromo-3-methyl-4-pentene 
• 90246-38-1 ((R)-1-Phenyl-ethyl)-carbamic acid (R)-1-(2-benzyloxy-ethyl)-prop-2-ynyl ester 
• 90246-37-0 ((R)-1-Phenyl-ethyl)-carbamic acid (S)-1-(2-benzyloxy-ethyl)-prop-2-ynyl ester 
• 90246-50-7 (S)-5-Benzyloxy-1-trimethylsilanyl-pent-1-yn-3-ol 
• 90319-48-5 (R)-5-(benzyloxy)-1-pentyn-3-ol 
• 90319-47-4 (3S)-5-(benzyloxy)pent-1-yn-3-ol 
• 91550-14-0 (2R)-4-(Benzyloxy)-2-methyl-1-butanal 

Downstream Products

• 90246-44-9 (1S ,7aS)-tetrahydro-1-methyl-1-<6-(benzyloxy)-4(R)-methyl-2-(trimethylsilyl)-2(Z)-hexenyl>-1H,3H-pyrrolo<1,2-c>oxazol-3-one 
• 374568-58-8 (R,E)-(5-(benzyloxy)-1-iodo-3-methylpent-1-enyl)trimethylsilane 
• 374568-59-9 (R,Z)-(7-(benzyloxy)-5-methylhept-3-en-3-yl)trimethylsilane 
• 374568-62-4 ((Z)-(R)-5-Iodo-3-methyl-hex-4-enyloxymethyl)-benzene 
• 374568-61-3 ((Z)-(R)-5-Iodo-3-methyl-hept-4-enyloxymethyl)-benzene 
• 374568-60-2 ((Z)-(R)-5-Benzyloxy-1,3-dimethyl-pent-1-enyl)-trimethyl-silane 
• 90246-49-4 (8S,8aS)-8-hydroxy-8-methyl-6(Z)-<6-oxo-2(R),5-dimethyl-7(R)-(tert-butyldiphenylsiloxy)-4(E)-octenylidene>octahydroindolizidine 
• 90246-46-1 (1S,7aS)-1-((Z)-(R)-6-Benzyloxy-4-methyl-2-trimethylsilanyl-hex-2-enyl)-1-methyl-tetrahydro-pyrrolo[1,2-c]oxazole 
• 90246-45-0 (8S,8aS)-8-hydroxy-8-methyl-6(Z)-<4-(benzyloxy)-2(R)-methylbutylidene>octahydroindolizidine 
• 67016-65-3 Pumiliotoxin B 

Relevant academic research and scientific papers

Total synthesis of (-)-callystatin A

(Chemical Equation Presented) A convergent enantioselective synthesis of the natural product (-)-callystatin A (1) is described. Key features of the synthesis include a lipase-mediated kinetic resolution to install the C5 lactone stereochemistry, a hydrozirconation-based approach to the C8-C9 trisubstituted (Z)-olefin, and a stereoselective cross-coupling of a vinyl dibromide to install the C14-C15 trisubstituted (E)-olefin.

Synthesis of indolizidines related to the carditonic pumiliotoxin a alkaloids

A method of making dendrobatid alkaloids with the formula STR1 in which A is either CH3 or H, and n is an integer from 1-9, and R is CH2 OH, CHO, STR2 and R1 and R2 are alkyl groups; and the use of such alkaloids to treat cardiovascular illness.