90273-67-9

Basic information

• Product Name: 3-(3,4-DICHLORO-PHENYL)-PROPIONYL CHLORIDE
• Synonyms: 3-(3,4-DICHLORO-PHENYL)-PROPIONYL CHLORIDE
• CAS NO: 90273-67-9
• Molecular Weight: 237.513
• Mol File: 90273-67-9.mol

Chemical Properties

• CAS DataBase Reference: 3-(3,4-DICHLORO-PHENYL)-PROPIONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,4-DICHLORO-PHENYL)-PROPIONYL CHLORIDE(90273-67-9)
• EPA Substance Registry System: 3-(3,4-DICHLORO-PHENYL)-PROPIONYL CHLORIDE(90273-67-9)

Safety Data

• Hazardous Substances Data: 90273-67-9(Hazardous Substances Data)

Upstream product

• 1202-39-7 3,4-dichlorocinnamic acid 
• 6287-38-3 3,4-dichlorobenzaldehyde 
• 115706-16-6 methyl 2-bromo-3-(3,4-dichlorophenyl)propionate 
• 115706-17-7 methyl 3‐(3,4‐dichlorophenyl)propanoate 
• 95-76-1 m,p-dichloroaniline 

Downstream Products

• 115706-18-8 1,2-dichloro-4-(2-isocyanatoethyl)benzene 
• 75416-52-3 6,7-dichloro-1,2,3,4-tetrahydroisoquinoline 
• 1429187-57-4 3-cyano-N-(3-(3,4-dichlorophenyl)propyl)-1-methyl-2-oxo-1,2-dihydroquinoline-4-carboxamide 
• 1429188-08-8 4-(3-(3,4-dichlorophenyl)propylcarbamoyl)-1-methyl-2-oxo-1,2-dihydroquinolin-3-yltrifluoromethanesulfonate 
• 1429187-50-7 N-(3-(3,4-dichlorophenyl)propyl)-1-methyl-3-(methylamino)-2-oxo-1,2-dihydroquinoline-4-carboxamide 
• 1429186-15-1 1-(4-bromophenyl)-N-(3-(3,4-dichlorophenyl)propyl)-3-hydroxy-2-oxo-1,2-dihydroquinoline-4-carboxamide 
• 1429187-96-1 methyl 2-(6-chloro-4-(3-(3,4-dichlorophenyl)propylcarbamoyl)-1-methyl-2-oxo-1,2-dihydroquinolin-3-yloxy)acetate 
• 1429185-46-5 2-(6-chloro-4-(3-(3,4-dichlorophenyl)propylcarbamoyl)-1-methyl-2-oxo-1,2-dihydroquinolin-3-yloxy)acetic acid 
• 1429187-95-0 6-chloro-N-(3-(3,4-dichlorophenyl)propyl)-3-methoxy-1-methyl-2-oxo-1,2-dihydroquinoline-4-carboxamide 
• 1429185-45-4 6-chloro-N-(3-(3,4-dichlorophenyl)propyl)-3-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-4-carboxamide 
• 1429185-43-2 N-(3-(3,4-dichlorophenyl)propyl)-3-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-4-carboxamide 
• 1429292-88-5 N-(3-(3,4-dichlorophenyl)propyl)-1-ethyl-5-oxo-4-((2-(pyridin-4-yl)ethyl)amino)-2,5-dihydro-1Hpyrrole-3-carboxamide 
• 1429292-84-1 N-(3-(3,4-dichlorophenyl)propyl)-1-ethyl-5-oxo-4-((3-(piperidin-1-yl)propyl)amino)-2,5-dihydro-1H-pyrrole-3-carboxamide 
• 1429292-86-3 N-(3-(3,4-dichlorophenyl)propyl)-1-ethyl-4-((2-isopropoxyethyl)amino)-5-oxo-2,5-dihydro-1Hpyrrole-3-carboxamide 

Relevant articles and documents

Benzo-aza-alkyl aryl piperazine derivative and applications in preparation of drugs

The invention discloses a benzo-aza-alkyl aryl piperazine derivative and applications in preparation of drugs. The derivative shows the effect on central nervous systems, especially on the double highaffinity activity of a 5-HT acceptor and a Sigma-1 acceptor. Various physiological and pharmacological effects are brought into play in the body; and the compound can be used as a pharmaceuticalactive substance, especially used for anti-depression, anti-anxiety, anti-bipolar affective disorder and anti-neuropathic pain, and can also be used as an intermediate to prepare other pharmaceuticalactive compounds. The compound is fast in effect and small in toxic and side effect, and can meet demands of clinical applications; and the compound is a compound or a free base or salt thereof havingthe following structural formula (IV). The structure of the compound or the free base or salt thereof is shown as the structural formula (IV).

Synthesis and Antileukemic Activity of Bismethyl>-Substituted Pyrroloisoquinolines, Pyrroloquinolines, Pyrroloisobenzazepines, and Pyrrolobenzazepines

A series of bismethyl>-substituted pyrrole-fused tricyclic heterocycles were synthesized by using 1,3-dipolar cycloaddition reactions with a trifluoromethanesulfonate salt of an appropriate Resissert compound or with a mesoionic oxazolone intermediate.All of the bis(carbamates) were active in vivo against P388 lymphocytic leukemia with 5,6-dihydro-8-methoxy-1,2-bis(hydroxymethyl)pyrroloisoquinoline bis (3c) showing the highest level of activity.