90322-37-5

Usage

Uses

Used in Pharmaceutical Industry:
2-Oxo-indoline-4-carboxylic acid is used as a key building block for the synthesis of various natural products and pharmaceutical compounds. Its unique structure allows for the creation of diverse bioactive molecules, contributing to the development of new drugs and therapeutic agents.
Used in Synthesis of Bioactive Molecules:
2-Oxo-indoline-4-carboxylic acid is utilized as a precursor in the synthesis of bioactive molecules, which have potential applications in treating a range of medical conditions. Its functional groups enable the formation of various chemical bonds, facilitating the creation of novel and effective pharmaceutical compounds.
Used in Treatment of Cancer:
2-Oxo-indoline-4-carboxylic acid has been studied for its potential role in the treatment of cancer. Its ability to interact with biological targets and modulate cellular pathways makes it a promising candidate for the development of anticancer drugs.
Used in Treatment of Infectious Diseases:
2-Oxo-indoline-4-carboxylic acid has also been investigated for its potential applications in treating infectious diseases. Its chemical properties allow it to target specific pathogens or modulate immune responses, offering a new avenue for the development of antimicrobial and antiviral agents.

Upstream product

• 215433-30-0 dimethyl 2-methoxycarbonyl-6-nitrophenyl-malonate 
• 7772-99-8 stannous chloride 
• 53553-14-3 2-chloro-3-nitrobenzoic acid methyl ester 
• 3970-35-2 2-chloro-3-nitrobezoic acid 
• 90924-46-2 2-oxo-2,3-dihydro-1H-indole-4-carboxylic acid methyl ester 
• 108-59-8 malonic acid dimethyl ester 
• 18107-18-1 diazomethyl-trimethyl-silane 

Downstream Products

• 342642-31-3 2-Oxo-2,3-Dihydro-1H-Indole-4-Carboxylic Acid (3-Chloro-4-Ethoxyphenyl)-Amide 

Relevant academic research and scientific papers

AMINOACYLINDAZOLE IMMUNOMODULATORS FOR TREATMENT OF AUTOIMMUNE DISEASES

2-Acylindazole compounds of formula I or formula II are disclosed. These compounds inhibit Coagulation Factor XIIa. They are useful to treat autoimmune diseases.

Combination therapy for the treatment of cancer

The present invention relates to methods for treatment or prevention of neoplasia disorders using protein tyrosine kinase inhibitors in combination with cyclooxygenase inhibitors, in particular cyclooxygenase-2 selective inhibitors.

Prodrugs of a 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives

The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

3-heteroarylidene-2-indolinone protein kinase inhibitors

The present invention relates to novel 3-heteroarylidene-2-indolinone compounds and physiologically acceptable salts thereof which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

3-(cycloalkanoheteroarylidenyl)-2-indolinone protein tyrosine kinase inhibitors

The present invention relates to novel 3-(cycloalkano-heteroarylidenyl)-2-indolinone compounds and physiologically acceptable salts and prodrugs thereof which are expected to modulate the activity of protein tyrosine kinases and therefore to be useful in the prevention and treatment of protein tyrosine kinase related cellular disorders such as cancer.

Pyrrole substituted 2-indolinone protein kinase inhibitors

The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

3-(cycloalkanoheteroarylidenyl)-2- indolinone protein tyrosine kinase inhibitors

The present invention relates to novel 3-(cycloalkanoheteroarylidenyl)-2-indolinone compounds and physiologically acceptable salts and prodrugs thereof which are expected to modulate the activity of protein tyrosine kinases and therefore to be useful in the prevention and treatment of protein tyrosine kinase related cellular disorders such as cancer.