90331-10-5Relevant articles and documents
1-AZADIENES AS A SYNTHON FOR HETEROCYCLIC SYNTHESIS
Ohshiro, Yoshiki,Komatsu, Mitsuo,Uesaka, Masatoshi,Agawa, Toshio
, p. 549 - 559 (2007/10/02)
1-Azabutadienes 1 were found to be a good building block for three- to five-membered heterocycles having a functional group.Oxidation of 1 with mCPBA afforded 3-alkenyloxaziridines 2.Cycloaddition of 1 with ketenes gave the 4-alkenylazetidinones 6.Addition of a nitrile imine occured across the C=N bond to give the 3-alkenyltriazoline 8, while that of a nitrile ylide occurred on the C=C bond to give the 3-formylpyrrole 14 formed by hydrolysis of the C=N bond.