90362-97-3Relevant academic research and scientific papers
Ortho -Naphthoquinone-catalyzed aerobic oxidation of amines to fused pyrimidin-4(3 H)-ones: A convergent synthetic route to bouchardatine and sildenafil
Kim, Hun Young,Kim, Kyeongha,Oh, Kyungsoo
, p. 31101 - 31105 (2020)
A facile access to fused pyrimidin-4(3H)-one derivatives has been established by using the metal-free ortho-naphthoquinone-catalyzed aerobic cross-coupling reactions of amines. The utilization of two readily available amines allowed a direct coupling strategy to quinazolinone natural product, bouchardatine, as well as sildenafil (Viagra) in a highly convergent manner. This journal is
A CONVENIENT SYNTHESIS OF GLYCOSMININE, 4-QUINAZOLINONE ALKALOID, AND RELATED COMPOUNDS
Ganjian, I.,Lalezari, I.
, p. 33 - 38 (2007/10/02)
Glycosminine or 2-(phenylmethyl)-4(3H)-quinazolinone, 6-methyl and 7-chloro derivatives as well as the related structural isomers 2-(4-methylphenyl)-4(3H)-quinazolinone, 6-methyl and 7-chloro compounds have been synthesized.
