904929-70-0Relevant academic research and scientific papers
Green approach: An efficient synthesis of 2,4-disubstituted-1,3-thiazoles and selenazoles in aqueous medium under ultrasonic irradiation
Ramesh, Gondru,Janardhan, Banothu,Rajitha, Bavantula
, p. 8099 - 8109 (2015/04/16)
An efficient and rapid procedure for the synthesis of 2,4-disubstituted-1,3-thiazoles and selenazoles has been described by the reaction of α-bromoketones with thiourea, phenylthiourea and selenourea at ambient temperature in aqueous medium under ultrasonic irradiation. Analytically pure products were formed within 10-60 s in excellent yields. The advantageous features of this non-conventional methodology over conventional methods are the operational simplicity, easy handling, yield-enhancing, time-reducing, mild reaction conditions and no by-product production.
A tandem one-pot aqueous phase synthesis of thiazoles/selenazoles
Madhav,Narayana Murthy,Anil Kumar,Ramesh,Nageswar
experimental part, p. 3835 - 3838 (2012/08/14)
The first ever tandem one-pot synthetic protocol for the synthesis of thiazoles/selenazoles from alkynes via the formation of 2,2-dibromo-1- phenylethanone is reported. The reaction is catalyzed by β-cyclodextrin in aqueous medium and resulted in good yields.
