90703-74-5Relevant articles and documents
SYNTHESIS AND PROPERTIES OF 1,4,9-TRIAZASPIROUNDECANE AND 3,7,11-TRIAZASPIRODODECANE
Kuroyan, R. A.,Sarkisyan, V. V.,Vartanyan, S. A.
, p. 1354 - 1357 (1986)
Bromination of 1-methylpiperidine-4-carboxaldehyde gave 4-bromo-1-methylpiperidine-4-carboxaldehyde hydrobromide which was used to synthesize 1,4,9-triazaspiroundecane and 3,7,11-triazaspirododecane.Cyanoethylation and alkylation with various alkyl halides gave their mono- and di-substituted derivatives.The side chain nitrile group was reduced and the hydrazide was obtained from the ester analog.