90712-41-7Relevant academic research and scientific papers
The ant-pro reverse-turn motif. Structural features and conformational characteristics
Thorat, Vijaykumar H.,Ingole, Tukaram S.,Vijayadas, Kuruppanthara N.,Nair, Roshna V.,Kale, Sangram S.,Ramesh, Veera V.E.,Davis, Hilda C.,Prabhakaran, Panchami,Gonnade, Rajesh G.,Gawade, Rupesh L.,Puranik, Vedavati G.,Rajamohanan, Pattuparambil R.,Sanjayan, Gangadhar J.
, p. 3529 - 3542 (2013/07/19)
This article details the characteristic conformational features of the Ant-Pro reverse turn - a folded pseudo β-turn motif that displays a closed nine-membered-ring hydrogen-bonded network involving just two amino acid residues, namely anthranilic acid (A
Discovery and optimization of a series of quinazolinone-derived antagonists of CXCR3
Johnson, Michael,Li, An-Rong,Liu, Jiwen,Fu, Zice,Zhu, Liusheng,Miao, Shichang,Wang, Xuemei,Xu, Qingge,Huang, Alan,Marcus, Andrew,Xu, Feng,Ebsworth, Karen,Sablan, Emmanuel,Danao, Jay,Kumer, Jeff,Dairaghi, Dan,Lawrence, Chris,Sullivan, Tim,Tonn, George,Schall, Thomas,Collins, Tassie,Medina, Julio
, p. 3339 - 3343 (2008/02/11)
A series of quinazolinone-derived inhibitors of the CXCR3 receptor have been synthesized and their affinity for the receptor evaluated. Compounds were evaluated in a 125I-IP10 displacement assay and in in vitro cell migration assays to IP10, IT
