908268-52-0

Basic information

• Product Name: Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester
• Synonyms: Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester;IMidazo[1,2-a]pyridine,7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-;Imidazo[1,2-a]pyridin-7-ylboronic acid pinacol ester;7-(tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridine;7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridine
• CAS NO: 908268-52-0
• Molecular Formula: C₁₃H₁₇BN₂O₂
• Molecular Weight: 244.1
• Product Categories: Organic boronic acid
• Mol File: 908268-52-0.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Density: 1.12±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 6.50±0.50(Predicted)
• CAS DataBase Reference: Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester(908268-52-0)
• EPA Substance Registry System: Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester(908268-52-0)

Safety Data

• Hazardous Substances Data: 908268-52-0(Hazardous Substances Data)

Usage

General Description

Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester is a chemical compound that belongs to the class of boronic acid esters. It contains an imidazo[1,2-a]pyridine ring fused with a boronic acid group. Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester has the potential to be used in various chemical reactions, such as Suzuki-Miyaura cross-coupling reactions, to introduce the imidazo[1,2-a]pyridine moiety into organic or pharmaceutical compounds. Boronic acid pinacol esters are known for their stability and easy handling, making them valuable reagents in organic synthesis. The imidazo[1,2-a]pyridine-7-boronic acid pinacol ester has the potential to be utilized in the development of new pharmaceuticals, agrochemicals, and materials due to the unique properties of the imidazo[1,2-a]pyridine ring. Further research and exploration of its potential applications are ongoing.

Upstream product

• 19798-80-2 2-Amino-4-chloropyridine 
• 107-20-0 2-chloroethanal 
• 1195995-72-2 4-(4,4,5 ,5-tetramethyl-1,3 ,2-dioxaborolan-2-yl)pyridin-2-amine 
• 84249-14-9 2-amino-4-bromopyridine 
• 73183-34-3 bis(pinacol)diborane 
• 808744-34-5 7-bromoimidazo[1,2-a]pyridine 
• 4532-25-6 7-chloroimidazo-[1,2-a]pyridine 

Downstream Products

• 1251863-05-4 1-[3-Isopropoxy-5-(7-pyrimidin-2-yl-imidazo[1,2-a]pyridin-3-yl)-phenyl]-3-(2,2,2-trifluoro-ethyl)-urea 

Relevant articles and documents

Transition metal complex, polymer, mixture, composition and organic electronic device

The invention discloses a transition metal complex, a polymer, a mixture, a composition and an organic electronic device. The transition metal complex has a structural general formula represented by achemical formula (1), and is simple to synthesize, novel in structure, relatively good in stability, long in service life and good in light emitting performance; the compound represented by the chemical formula (1) is convenient for realizing an efficient, high-brightness and high-stability OLED device, and a relatively good material option is provided for full-color display and illumination application.

Imidazo [1,2-a] pyridine-6-boronic acid frequency ester and its derivatives preparation method

The invention discloses preparation methods for imidazole[1,2-a]pyridine-6-boric acid pinacol ester and derivatives thereof. The preparation methods comprise a preparation method for imidazole[1,2-a]pyridine-6-boric acid pinacol ester, a preparation method for imidazole[1,2-a]pyridine-7-boric acid pinacol ester and a preparation method for imidazole[1,2-a]pyridine-8-boric acid pinacol ester. The imidazole[1,2-a]pyridine-6-boric acid pinacol ester and derivatives thereof prepared by using the preparation methods are used in the Suzuki coupling reaction for a coupling reaction with compounds like halides and TfO-R. According to a technical scheme in the invention, the preparation methods have the advantages of high reaction yield, easy purification, suitability for production, etc.

IMIDAZO [1,2-A]PYRIDINE DERIVATIVES AS FGFR KINASE INHIBITORS FOR USE IN THERAPY

The invention relates to new bicyclic heterocyclyl derivatives of formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.