908268-52-0

Basic information

• Product Name: Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester
• Synonyms: Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester;IMidazo[1,2-a]pyridine,7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-;Imidazo[1,2-a]pyridin-7-ylboronic acid pinacol ester;7-(tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridine;7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridine
• CAS NO: 908268-52-0
• Molecular Formula: C₁₃H₁₇BN₂O₂
• Molecular Weight: 244.1
• Product Categories: Organic boronic acid
• Mol File: 908268-52-0.mol

Chemical Properties

• Appearance: /
• Density: 1.12±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 6.50±0.50(Predicted)
• CAS DataBase Reference: Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester(908268-52-0)
• EPA Substance Registry System: Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester(908268-52-0)

Safety Data

• Hazardous Substances Data: 908268-52-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester is used as a reagent in various chemical reactions, such as Suzuki-Miyaura cross-coupling reactions, for the introduction of the imidazo[1,2-a]pyridine moiety into organic or pharmaceutical compounds. Its stability and easy handling make it a preferred choice in organic synthesis.
Used in Pharmaceutical Development:
Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester is utilized in the development of new pharmaceuticals due to the unique properties of the imidazo[1,2-a]pyridine ring. Its potential applications in drug discovery are being explored for the creation of novel therapeutic agents.
Used in Agrochemical Development:
Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester is also used in the development of new agrochemicals, where the imidazo[1,2-a]pyridine ring may contribute to the design of effective and targeted pesticides or other agricultural products.
Used in Material Science:
Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester has the potential to be utilized in the development of new materials, capitalizing on the structural and functional attributes of the imidazo[1,2-a]pyridine system to create innovative materials with specific properties.
Further research and exploration of Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester's potential applications are ongoing across these industries, indicating its broad utility and the possibility of future discoveries in its application space.

Upstream product

• 4532-25-6 7-chloroimidazo-[1,2-a]pyridine 
• 73183-34-3 bis(pinacol)diborane 
• 19798-80-2 2-Amino-4-chloropyridine 
• 107-20-0 2-chloroethanal 
• 1195995-72-2 4-(4,4,5 ,5-tetramethyl-1,3 ,2-dioxaborolan-2-yl)pyridin-2-amine 
• 84249-14-9 2-amino-4-bromopyridine 
• 808744-34-5 7-bromoimidazo[1,2-a]pyridine 

Downstream Products

• 1251863-05-4 1-[3-Isopropoxy-5-(7-pyrimidin-2-yl-imidazo[1,2-a]pyridin-3-yl)-phenyl]-3-(2,2,2-trifluoro-ethyl)-urea 

Relevant articles and documents

Transition metal complex, polymer, mixture, composition and organic electronic device

The invention discloses a transition metal complex, a polymer, a mixture, a composition and an organic electronic device. The transition metal complex has a structural general formula represented by achemical formula (1), and is simple to synthesize, novel in structure, relatively good in stability, long in service life and good in light emitting performance; the compound represented by the chemical formula (1) is convenient for realizing an efficient, high-brightness and high-stability OLED device, and a relatively good material option is provided for full-color display and illumination application.

IMIDAZO [1,5-A]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS

The invention provides substituted imidazo[1,5-a]pyrimidinyl carboxamide and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted imidazo[1,5-a]pyrimidinyl carboxamide compounds described herein include substituted 2-heterocyclyl-4-alkyl-imidazo[1,5-a]pyrirnidine-8-carboxamide compounds and variants thereof.

Imidazo [1,2-a] pyridine-6-boronic acid frequency ester and its derivatives preparation method

The invention discloses preparation methods for imidazole[1,2-a]pyridine-6-boric acid pinacol ester and derivatives thereof. The preparation methods comprise a preparation method for imidazole[1,2-a]pyridine-6-boric acid pinacol ester, a preparation method for imidazole[1,2-a]pyridine-7-boric acid pinacol ester and a preparation method for imidazole[1,2-a]pyridine-8-boric acid pinacol ester. The imidazole[1,2-a]pyridine-6-boric acid pinacol ester and derivatives thereof prepared by using the preparation methods are used in the Suzuki coupling reaction for a coupling reaction with compounds like halides and TfO-R. According to a technical scheme in the invention, the preparation methods have the advantages of high reaction yield, easy purification, suitability for production, etc.

FATTY ACID SYNTHASE INHIBITORS

This invention relates to novel spirocyclic piperidines according to Formula (I) which are inhibitors of fatty acid synthase (FAS), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.

IMIDAZO [1,2-A]PYRIDINE DERIVATIVES AS FGFR KINASE INHIBITORS FOR USE IN THERAPY

The invention relates to new bicyclic heterocyclyl derivatives of formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

IMIDAZOPYRIDINE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSINE KINASES

The invention relates to new bicyclic heterocyclic derivative compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

CYCLOHEXYLPYRAZOLE-LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1

The present invention discloses novel compounds of Formula (I): having 11β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compound

IMIDAZO (1, 2-A) PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS

The present invention provides compounds that are inhibitors of VEGF-R2 of the formula: (I) and methods of using these compounds.