90844-13-6Relevant academic research and scientific papers
Ester derivatives and medicinal use thereof
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Page/Page column 41, (2010/11/08)
The present invention relates to an ester represented by the formula [1]: or its pharmaceutically acceptable salt, or use of the same. The compound represented by the formula [1] or its pharmaceutically acceptable salt is useful as an agent for the treatment or prophylaxis of hyperlipidemia or the like, since it disappears very rapidly in the living body and has an excellent MTP inhibitory activity.
Benzopyrones. Part 22. Synthesis of New 4-Oxochromene Polycarboxylic Acids
Ellis, Gwynn P.,Hudson, Henrietta V.
, p. 3830 - 3860 (2007/10/02)
The synthesis of the following chromone dicarboxylic acids is described: 4-oxochromene-2,7-dicarboxylic acid, 6-methyl-4-oxochromene-2,8-dicarboxylic acid, 7-hydroxy-4-oxochromene-2,8-dicarboxylic acid, and 4-oxochromene-3,6-dicarboxylic acid. 4-Oxochromene-2,3-dicarboxylic acid 2-ethyl ester has been synthesized as well as 4-oxochromene-2,6,8-tricarboxylic acid.Some derivatives of these acids are described and the relative stability of carboxy groups attached to the chromen-4-one ring system is discussed.
