909720-32-7

Upstream product

• 40473-07-2 6-bromo-2-methoxypyridine 
• 909720-24-7 2-isopropyl-7-methoxypyrazolo[1,5-a]pyridine-4-boric acid 
• 1332861-58-1 C₁₃H₁₉BN₂O₃ 
• 909720-23-6 4-bromo-2-isopropyl-7-methoxypyrazolo[1,5-a]pyridine 
• 1312815-90-9 C₉H₁₁O₃S^(1-)*C₁₁H₁₄BrN₂O⁽¹⁺⁾ 
• 909720-22-5 3-bromo-6-methoxy-2-(3-methyl-1-butynyl)pyridine 
• 909720-21-4 2,3-dibromo-6-methoxypyridine 
• 909720-36-1 6-(7-methoxy-2-isopropylpyrazolo[1,5-a]pyridine-4-yl)-3(2H)pyridazinone 
• 100-39-0 benzyl bromide 
• 909720-28-1 4-(6-chloropyridazine-3-yl)-7-methoxy-2-isopropyl-pyrazolo[1,5-a]pyridine 

Downstream Products

• 909720-44-1 C₂₂H₂₄N₄O₂ 

Relevant academic research and scientific papers

Phosphodiesterase inhibitors. Part 1: Synthesis and structure-activity relationships of pyrazolopyridine-pyridazinone PDE inhibitors developed from ibudilast

Ibudilast [1-(2-isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one] is a nonselective phosphodiesterase inhibitor used clinically to treat asthma. Efforts to selectively develop the PDE3- and PDE4-inhibitory activity of ibudilast led to replacemen

Pyrazolopyridine-4-Yl Pyridazinone Derivatives and Addition Salts Thereof, and Pde Inhibitors Comprising the Same Derivatives or Salts as Active Ingredient

Novel pyrazolopyridine-4-yl pyridazinone derivatives serve as phosphodiesterase inhibitors and are useful compounds for use in pharmaceutical products. Specifically, the compounds of the present invention are pyrazolopyridine-4-yl pyridazinone derivatives represented by the following general formula (1): (Example: 6-(2-ethyl-7-methoxy-pyrazolo[1,5-a]pyridine-4-yl)-5-methyl-4, 5-dihydro-3(2H)-pyridazinone).