910138-87-3

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 62681-68-9 1-(benzo[d][1,3]dioxol-5-yl)ethan-1-one oxime 
• 524939-61-5 1-[(4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl]-1-[(tert-butyldimethylsilyloxy)methyl]-2-propen-1-ol 
• 524939-62-6 4-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dimethyl-4,6a-dihydro-3aH-cyclopenta[1,3]dioxol-4-ol 
• 1040271-74-6 4-(tert-butyl-dimethyl-silanyloxymethyl)-6-chloro-2,2-dimethyl-4,6a-dihydro-3aH-cyclopenta[1,3]dioxol-4-ol 
• 1040272-26-1 6-chloro-4-hydroxymethyl-2,2-dimethyl-4,6a-dihydro-3aH-cyclopenta[1,3]dioxol-4-ol 
• 3162-29-6 1-(benzo[d][1,3]dioxol-6-yl)ethanone 
• 62681-67-8 2-(benzo[1,3]dioxol-5-yl)aziridine 
• 910138-81-7 C₃₁H₃₅NO₈S 
• 910138-85-1 C₂₈H₂₉NO₇ 
• 910138-82-8 C₂₅H₃₁NO₆ 
• 910138-80-6 C₂₁H₂₇NO₅Si 
• 910138-83-9 C₂₀H₂₃NO₅ 
• 910138-79-3 C₁₇H₁₇NO₅ 

Downstream Products

• 910138-88-4 C₃₀H₃₁NO₉ 
• 1040272-38-5 (1S,3aR,14bS)-2-methoxy-1,5,6,8,9,14b-hexahydro-4H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]cyclopenta[b]pyrrolo[1,2-a]azepin-1-yl (R)-2-((E)-4-(benzyloxy)-4-methylpent-2-en-1-yl)-4-oxooxetane-2-carboxylate 
• 1040272-14-7 1-((1S,3aR,14bS)-2-methoxy-1,5,6,8,9,14b-hexahydro-4H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]cyclopenta[b]pyrrolo[1,2-a]azepin-1-yl) 4-methyl (R)-2-((E)-4-(benzyloxy)-4-methylpent-2-en-1-yl)-2-hydroxysuccinate 
• 38750-57-1 (-)-Cephalotaxinone 
• 36804-95-2 deoxyharringtonine 

Relevant academic research and scientific papers

CEPHALOTAXUS ESTERS, METHODS OF SYNTHESIS, AND USES THEREOF

The present invention provides novel cephalotaxus esters, syntheses thereof, and intermediates thereto. The invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of using said compounds or compositions in the treatment of proliferative diseases (e.g., benign neoplasm, cancer, inflammatory disease, autoimmune disease, diabetic retinopathy) and infectious disease. The invention further provides methods of using said compounds or compositions in the treatment of multidrug resistant cancer.