91021-08-8Relevant academic research and scientific papers
Eco-friendly Polyethylene Glycol-400 as a Rapid and Efficient Recyclable Reaction Medium for the Synthesis of Anticancer Isatin-linked Chalcones and Their 3-Hydroxy Precursor
Gupta, Alpana K.,Bharadwaj, Mausumi,Mehrotra, Ravi
, p. 703 - 709 (2018/12/11)
Isatin chalcones and their 3-hydroxy precursors are shown to possess potential anticancer activity and are also versatile substrates and key intermediates for the synthesis of a large variety of bioactive spiro-oxindoles. An environmental friendly tandem
Glucose-containing imidazolium salt-catalyzed cross-aldol reaction of isatins and unactivated ketones
Wan, Yu,Yuan, Rui,Cui, Hao,Zhang, Xiao-xiao,Li, Ming-qi,Xu, Jiang-biao,Dou, Peng-fei,Zhang, Long-yan,Wu, Hui
, p. 2561 - 2570 (2018/02/16)
Ketone–ketone cross-aldol reaction of isatins and unactivated ketones was catalyzed by glucose-containing imidazolium salt β-1-imidazole-2,3,4,6-tetra-o-hydroxy-d-glucopyranosyl bromide in neutral condition to generate 3-alkyl-3-hydroxyindolin-2-ones in e
Bromo β - 1 - imidazole - 2, 3, 4, 6 - tetrahydroxy - D - pyran glucose synthesis and use (by machine translation)
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Paragraph 0044; 0045; 0046; 0047; 0048-0050; 0053-0056, (2017/07/04)
A bromo β - 1 - imidazole - 2, 3, 4, 6 - tetrahydroxy - D - pyran glucose synthesis and use, which belongs to the multi-component reaction chemical synthesis pyran glucose and use thereof. Bromo β - 1 - imidazole - 2, 3, 4, 6 - tetrahydroxy - D - pyran gl
Ordered short channel mesoporous silica modified with 1,3,5-triazine-piperazine as a versatile recyclable basic catalyst for cross-aldol, Knoevenagel and conjugate addition reactions with isatins
Gupta, Naveen,Roy, Tamal,Ghosh, Debashis,Abdi, Sayed H. R.,Kureshy, Rukhsana I.,Khan, Noor-Ul H.,Bajaj, Hari C.
, p. 17843 - 17850 (2015/03/04)
A triazine-piperazine immobilized on ordered short channel mesoporous silica was synthesized, characterized and used as a heterogeneous basic catalyst in the synthesis of indole skeletal structures from isatin derivatives under ambient reaction conditions in good to excellent isolated yields. The catalyst showed no loss in its efficacy over 10 recycle experiments. This journal is
C U 2O-Catalyzed C(SP 3)-H/C(SP 3)-H Cross-Coupling Using TEMPO: Synthesis of 3-(2-Oxoalkyl)-3-hydroxyoxindoles
Wang, Baoshuang,Zhu, Jiayi,Wei, Yang,Luo, Guotian,Qu, Hongen,Liu, Liang-Xian
, p. 2841 - 2848 (2015/12/23)
A simple, convenient, and efficient oxidative cross-coupling reaction of oxindoles with ketones toward a variety of 3-(2-oxoalkyl)-3-hydroxyoxindoles in moderate to excellent yields has been developed. This transformation proceeds via a tandem oxidative cross-coupling by using 2,2,6,6-tetramethylpiperidine N-oxyl (TEMPO) in air as an environmentally benign oxidant. This methodology provides an alternative approach for the direct generation of all-carbon quaternary centers at the C3 position of oxindoles.
