911303-07-6Relevant academic research and scientific papers
Catalyst-free synthesis of 3-(1-arylsulfonylalkyl)indoles via three-component reaction of indoles, carbonyls, and arenesulfinic acids
Huang, Wenzhong,Yang, Juan,Li, Xiangguang,Yuan, Lin,Ma, Yinhai,Zhou, Qinglong,Liang, Deqiang
supporting information, p. 772 - 777 (2016/05/09)
A catalyst-free three-component reaction of indoles, carbonyls, and arenesulfinic acids performed at room temperature provides direct access to biologically important 3-(1-arylsulfonylalkyl)indoles. This process features mild conditions, low cost, broad s
Highly enantioselective monofluoromethylation of C2-arylindoles using FBSM under chiral phase-transfer catalysis
Matsuzaki, Kohei,Furukawa, Tatsuya,Tokunaga, Etsuko,Matsumoto, Takashi,Shiro, Motoo,Shibata, Norio
, p. 3282 - 3285 (2013/07/26)
The highly enantioselective addition of 1-fluoro-1,1-bis(phenylsulfonyl) methane (FBSM) to vinylogous imines generated in situ from 2-aryl-3-(1- arylsulfonylmethyl)indoles was achieved using chiral ammonium salts derived from cinchona alkaloids. One-pot c
Highly enantioselective michael addition of malononitrile to vinylogous imine intermediates generated in situ from arylsulfonyl indoles
Jing, Linhai,Wei, Jiangtao,Zhou, Li,Huang, Zhiyong,Li, Zhengkai,Wu, Di,Xiang, Haifeng,Zhou, Xiangge
supporting information; experimental part, p. 10955 - 10958 (2010/11/05)
(Figure Presented) Malononitrile on rare form: Highly enantioselective Michael addition of malononitrile to vinylogous imine intermediates 2, generated in situ from arylsulfonyl indoles 1, is described (see scheme). This protocol provides easy and conveni
Amberlyst-15: an efficient and reusable catalyst for the Friedel-Crafts reactions of activated arenes and heteroarenes with α-amido sulfones
Kadam, Santosh T.,Thirupathi, Ponnaboina,Kim, Sung Soo
experimental part, p. 10383 - 10389 (2010/02/27)
The heterogeneous Amberlyst-15 catalyst displays efficient catalytic properties for the Friedel-Crafts reactions between an activated arenes or heteroarenes and α-amido sulfones. Various α-amido sulfones on treatment with 1,2,4-trimethoxy benzene give the
InBr3: A versatile catalyst for the different types of Friedel-Crafts reactions
Thirupathi, Ponnaboina,Sung, Soo Kim
scheme or table, p. 7755 - 7761 (2009/12/27)
(Chemical Equation Presented) Mild and efficient InBr3-catalyzed Friedel-Crafts alkylation of heteroaromatic or electron-rich aromatic compounds with α-amido sulfones at room temperature in CH2Cl2 has been developed. The p
Simplified synthesis of 3-(1-arylsulfonylalkyl) indoles and their reaction with reformatsky reagents
Palmieri, Alessandro,Petrini, Marino
, p. 1863 - 1866 (2007/10/03)
A simple procedure for the preparation of 3-(1-arylsulfonylalkyl) indoles by three-component condensation of indoles, carbonyls, and arenesulfinic acids is presented. The obtained products undergo a Reformatsky reaction leading to alkyl 3-(3-indolyl) alka
Solventless clay-promoted Friedel-Crafts reaction of indoles with α-amido sulfones: Unexpected synthesis of 3-(1-arylsulfonylalkyl) indoles
Ballini, Roberte,Palmieri, Alessandro,Petrini, Marino,Torregiani, Elisabetta
, p. 4093 - 4096 (2007/10/03)
Friedel-Crafts reaction of indoles with α-amido sulfones in the presence of montmorillonite K-10 leads unexpectedly to 3-(1-arylsulfonylalkyl) indoles in good yield. The obtained products can be further desulfonylated under reductive or alkylative conditi
