911814-61-4

Basic information

• Product Name: 1H-Indole-2-carboxylic acid, 3-methoxy-1-[3-(1-methylethyl)phenyl]-, ethyl ester
• CAS NO: 911814-61-4
• Molecular Formula: C21H23NO3
• Molecular Weight: 337.419
• Mol File: 911814-61-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Indole-2-carboxylic acid, 3-methoxy-1-[3-(1-methylethyl)phenyl]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-2-carboxylic acid, 3-methoxy-1-[3-(1-methylethyl)phenyl]-, ethyl ester(911814-61-4)
• EPA Substance Registry System: 1H-Indole-2-carboxylic acid, 3-methoxy-1-[3-(1-methylethyl)phenyl]-, ethyl ester(911814-61-4)

Safety Data

• Hazardous Substances Data: 911814-61-4(Hazardous Substances Data)

Upstream product

• 14370-74-2 ethyl 3-hydroxy-1H-indole-2-carboxylate 
• 134-20-3 2-carbomethoxyaniline 
• 13622-59-8 N-(2-methoxycarbonylphenyl)glycine methyl ester 
• 15936-44-4 3-methoxy-1H-indole-2-carboxylic acid ethyl ester 
• 216019-28-2 3-isopropylphenylboronic acid 

Downstream Products

• 911818-21-8 1-(3-isopropyl-phenyl)-3-(4-trifluoromethyl-phenoxy)-1H-indole-2-carboxylic acid ethyl ester 
• 911818-15-0 1-(3-isopropyl-phenyl)-3-(3-trifluoromethyl-phenoxy)-1H-indole-2-carboxylic acid ethyl ester 
• 911818-22-9 3-(3-hydroxy-phenoxy)-1-(3-isopropyl-phenyl)-1H-indole-2-carboxylic acid ethyl ester 
• 911815-63-9 3-hydroxy-1-(3-isopropyl-phenyl)-1H-indole-2-carboxylic acid ethyl ester 

Relevant articles and documents

Synthesis and biological activities of novel aryl indole-2-carboxylic acid analogs as PPARγ partial agonists

A series of novel aryl indole-2-carboxylic acids has been identified as potent selective PPARγ modulators. Their chemical synthesis and in vitro activities are discussed. Compound 5 was selected for in vivo testing in the db/db mouse model of type 2 diabetes and resulted in reduction of hyperglycemia at comparable plasma exposure when compared to rosiglitazone.