91229-86-6

Basic information

• Product Name: 5-Bromo-N-[(tert-butoxy)carbonyl]-L-norvaline tert-butyl ester
• Synonyms: 5-Bromo-N-[(tert-butoxy)carbonyl]-L-norvaline tert-butyl ester;(S)-tert-Butyl 5-broMo-2-((tert-butoxycarbonyl)aMino)pentanoate
• CAS NO: 91229-86-6
• Molecular Formula: C₁₄H₂₆BrNO₄
• Molecular Weight: 352.26454
• Mol File: 91229-86-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 402.7±40.0 °C(Predicted)
• Appearance: /
• Density: 1.218
• Storage Temp.: 2-8°C
• PKA: 11.05±0.46(Predicted)
• CAS DataBase Reference: 5-Bromo-N-[(tert-butoxy)carbonyl]-L-norvaline tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-N-[(tert-butoxy)carbonyl]-L-norvaline tert-butyl ester(91229-86-6)
• EPA Substance Registry System: 5-Bromo-N-[(tert-butoxy)carbonyl]-L-norvaline tert-butyl ester(91229-86-6)

Safety Data

• Hazardous Substances Data: 91229-86-6(Hazardous Substances Data)

Usage

General Description

5-Bromo-N-[(tert-butoxy)carbonyl]-L-norvaline tert-butyl ester is a compound with the chemical formula C13H25BrNO4. It is a derivative of L-norvaline, an amino acid, and is often used as a building block in organic synthesis. 5-Bromo-N-[(tert-butoxy)carbonyl]-L-norvaline tert-butyl ester is a white to off-white solid that is typically used in research and development of pharmaceuticals and agrochemicals. It is also commonly used as a reagent in chemical reactions to introduce the tert-butoxy carbonyl (Boc) protecting group onto amino acids, which can then be cleaved later in the synthesis process. Additionally, this compound has been studied for its potential biological activity and pharmacological properties in the context of drug discovery. Overall, 5-Bromo-N-[(tert-butoxy)carbonyl]-L-norvaline tert-butyl ester is an important chemical compound in the fields of organic chemistry and drug development.

Upstream product

• 132245-78-4 (S)-2-tert-butoxycarbonylaminopentanedioic acid 1-benzyl ester 5-methyl ester 
• 30924-93-7 Boc-Glu-OBn 
• 28812-54-6 α-tert-butyl γ-benzyl N^α-(tert-butyloxycarbonyl)-L-glutamate 
• 24277-39-2 α-tert-butyl N^α-(tert-butyloxycarbonyl)-L-glutamate 
• 1676-73-9 glutamic acid γ-benzyl ester 
• 80165-23-7 2-Amino-pentanedioic acid 5-benzyl ester 1-tert-butyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 45214-91-3 (2S)-2-[(tert-butoxy)carbonylamino]-4-(methoxycarbonyl)butanoic acid 
• 1499-55-4 L-glutamic acid 5-methyl ester 
• 56-86-0 L-glutamic acid 
• 212121-62-5 1-tert-butyl 5-methyl (S)-2-((diphenylmethylene)amino)pentanedioate 
• 24277-38-1 (S)-(-)-1-tert-butyl-5-methyl-<(2-tert-butoxycarbonyl)amino>pentanedioate 
• 81477-94-3 N-(diphenylmethylene)glycine tert-butyl ester 
• 79640-72-5 L-glutamic acid 1-tert-butyl ester 5-methyl ester 

Downstream Products

• 37513-14-7 N^δ-tosyl-N^δ-(benzyloxy)-L-ornithine 
• 56-87-1 L-lysine 
• 91237-84-2 N-Boc-L-proline tert-butyl ester 
• 91229-89-9 5-(N-Benzyloxy-acetimidoyloxy)-2-tert-butoxycarbonylamino-pentanoic acid tert-butyl ester 
• 91229-88-8 5-(N-Benzyloxy-acetimidoyloxy)-2-tert-butoxycarbonylamino-pentanoic acid tert-butyl ester 
• 90195-02-1 α-tert-butyl N^α-(tert-butyloxycarbonyl)-N^δ-acetyl-N^δ-(benzyloxy)-L-ornithine 
• 91229-90-2 α-tert-butyl N^α-(tert-butyloxycarbonyl)-N^δ-tosyl-N^δ-(benzyloxy)-L-ornithine 

Relevant articles and documents

METHOD FOR PRODUCING DESMOSINE, ISODESMOSINE AND DERIVATIVES THEREOF

A process for preparing a compound represented by the following general formula (I) or a salt thereof, which comprises reacting lysine or a protective product thereof or a salt thereof with allysine or a protective product thereof in the presence of a spe

Synthesis of (ε-13C-,ε-15N)-enriched L-lysine - Establishing schemes for the preparation of all possible 13C and 15N isotopomers of L-lysine, L-ornithine, and L-proline

In this paper we describe a simple synthetic strategy that, with the right rational adaptation, gives direct access to any 13C/15N isotopomer of L-glutamate, L-ornithine, L-proline, L-lysine, and L-α, amino adipic acid. This strategy also allows access to nonproteinogenic amino acids like L-citrulline in high yields and optical purity. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.

Facile new method for preparation of optically active protected proline

Treatment of L-N-protected 2-amino-5-bromopentanoic acid ester, which was prepared from protected L-glutamic acid, with sodium hydride in tetrahydrofuran (THF) proceeded to give the corresponding protected L-proline in high yield. On the other hand, the reaction of 2-aminobutyric acid derivative with sodium hydride gave the 1-aminocyclopropane-1-carboxylic acid derivative.