91241-12-2

Basic information

• Product Name: N,N,N',N'-TETRAMETHYL-N''-[TRIS(DIMETHYLAMINO)PHOSPHORANYLIDENE]PHOSPHORIC TRIAMIDE
• Synonyms: N,N,N',N'-TETRAMETHYL-N''-[TRIS(DIMETHYLAMINO)PHOSPHORANYLIDENE]PHOSPHORIC TRIAMIDE;1,1,3,3,3-Pentakis(dimethylamino)-1lambda5,3lambda5-diphosphazene 1-oxide;1,1,3,3,3-pentakis(dimethylamino)-di-phosphazene 1-oxide;TETRAMETHYL(TRIS(DIMETHYLAMINO)PHOSPHOR- ANYLIDENE)PHOSPHORIC TRIAMIDE, 98%;methyl(dimethylamino)phosphoranylidene phosphoric triamide;1,1,3,3,3-Pentakis(dimethylamino)-1λ:5,3λ:5-diphosphazene 1-oxide;PDPO;1,1,3,3,3-Pentakis(dimethylamino)-1λ5,3λ5-diphosphazene 1-oxide 98%
• CAS NO: 91241-12-2
• Molecular Formula: C₁₀H₃₀N₆OP₂
• Molecular Weight: 312.33
• Mol File: 91241-12-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 348 °C(lit.)
• Flash Point: 211 °F
• Appearance: /
• Density: 1.07 g/mL at 25 °C(lit.)
• Vapor Pressure: 3.24E-05mmHg at 25°C
• Refractive Index: n20/D 1.495(lit.)
• CAS DataBase Reference: N,N,N',N'-TETRAMETHYL-N''-[TRIS(DIMETHYLAMINO)PHOSPHORANYLIDENE]PHOSPHORIC TRIAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N,N',N'-TETRAMETHYL-N''-[TRIS(DIMETHYLAMINO)PHOSPHORANYLIDENE]PHOSPHORIC TRIAMIDE(91241-12-2)
• EPA Substance Registry System: N,N,N',N'-TETRAMETHYL-N''-[TRIS(DIMETHYLAMINO)PHOSPHORANYLIDENE]PHOSPHORIC TRIAMIDE(91241-12-2)

Safety Data

• Hazard Codes: C
• Statements: 34-37
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3267 8/PG 2
• WGK Germany: 3
• F: 3-10
• Hazardous Substances Data: 91241-12-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H30N6OP2/c1-12(2)18(13(3)4,14(5)6)11-19(17,15(7)8)16(9)10/h1-10H3

Upstream product

• 124-38-9 carbon dioxide 
• 165535-45-5 1-ethyl-2,2,4,4,4-pentakis(dimethylamino)-2λ⁵,4λ⁵-catenadi(phosphazene) 
• 49778-01-0 iminotris(dimethylamino)phosphorane 
• 1605-65-8 N,N,N',N'-Tetramethylphosphorodiamidic chloride 

Relevant articles and documents

Automated solid-phase radiofluorination using polymer-supported phosphazenes

The polymer supported phosphazene bases PS-P2 tBu and the novel PS-P2 PEG allowed for efficient extraction of [18F]F- from proton irradiated [18O]H 2O and subsequent radiofluorination of a broad range of substrates directly on the resin. The highest radiochemical yields were obtained with aliphatic sulfonates (69%) and bromides (42%); the total radiosynthesis time was 35-45 min. The multivariate analysis showed that the radiochemical yields and purities were controlled by the resin load, reaction temperature, and column packing effects. The resins could be reused several times with the same or different substrates. The fully automated on-column radiofluorination methodology was applied to the radiosynthesis of the important PET radiotracers [18F]FLT and [18F]FDG. The latter was produced with 40% yield on a 120 GBq scale and passed GMP-regulated quality control required for commercial production of [18F]FDG. The combination of compact form factor, simplicity of [18F]F- recovery and processing, and column reusability can make solid phase radiofluorination an attractive radiochemistry platform for the emerging dose-on-demand instruments for bedside production of PET radiotracers.

Phosphazenes: Efficient organocatalysts for the catalytic hydrosilylation of carbon dioxide

Phosphazene superbases are efficient organocatalysts for the metal-free catalytic hydrosilylation of carbon dioxide. They react with CO2 to form the respective phosphine oxides, but in the presence of hydrosilanes, CO2 can be selectively reduced to silyl formates, which can in turn be reduced to methoxysilanes by addition of an extra loading of silanes. Activities reach a TOF of 32 h-1 with a TON of 759. It is also shown that unexpectedly, N,N-dimethylformamide can reduce CO2 to a mixture of silyl formates, acetals and methoxides in the absence of any catalyst.