91250-65-6

Upstream product

• 93-55-0 1-phenyl-propan-1-one 
• 121-45-9 phosphorous acid trimethyl ester 
• 98-88-4 benzoyl chloride 
• 18106-71-3 dimethyl benzoylphosphonate 
• 97-93-8 triethylaluminum 
• 96-36-6 methyl phosphite 
• 868-85-9 Dimethyl phosphite 

Relevant academic research and scientific papers

The catalytic aerobic synthesis of quaternary α-hydroxy phosphonates via direct hydroxylation of phosphonate compounds

A highly efficient Cu-catalyzed direct hydroxylation of phosphonate compounds has been developed. This transformation provides a powerful method for the synthesis of quaternary α-hydroxy phosphonates in good yields. The direct transformation process, regiospecific selectivity, and good tolerance to a variety of substituents make it an alternative approach to the reported protocols.

Ultrasound assisted green synthesis of α-hydroxyphosphonates under solvent-free conditions

Abstract: A simple, efficient and environmentally benign method for the synthesis of α-hydroxyphosphonates by reaction of an aldehyde or a ketone, and trialkylphosphite is effectively accomplished under ultrasound irradiation and solvent-free and catalyst

C-H hydroxylation of phosphonates with oxygen in [bmIm]OH to produce quaternary α-hydroxy phosphonates

A highly efficient and mild [bmIm]OH-catalyzed α-hydroxylation of phosphonates using O2 as the oxygen source is described. The employment of ionic liquid under mild reaction conditions makes this transformation green and practical. Especially, this reaction provided a novel and convenient methodology for the construction of quaternary α-hydroxy phosphonates.

Synthesis of quaternary α-hydroxy phosphonates via direct hydroxylation of phosphonate compounds

It was found for the first time that Cs2CO3 serves as highly efficient catalyst for the direct hydroxylation reactions of phosphonates under mild conditions. This reaction provides an efficient approach to quaternary α-hydroxy phosph

Reactions of acyl phosphonates with organoaluminum reagents: A new method for the synthesis of secondary and tertiary α-hydroxy phosphonates

The reactions of organoaluminum reagents (trimethylaluminum, triethylaluminum, etc.) with aryl and alkyl acyl phosphonates, which lead to the formation of α-hydroxy phosphonates in moderate to good yields, are reported. This method provides easy access to

Highly efficient synthesis of quaternary α-hydroxy phosphonates via lewis acid-catalyzed hydrophosphonylation of ketones

A Lewis acid catalyst has been first applied to the hydrophosphonylation of ketones, giving the corresponding quaternary a-hydroxy phosphonates in high yields (up to 98%). The present method was highly tolerable for functionalized ketones. Moreover, the f

AN UNEXPECTED REACTIVITY OF SIMPLE HETEROGENEOUS MIXTURE OF γ-ALUMINA AND POTASSIUM FLUORIDE : 1-HYDROXYALKANE PHOSPHONIC ESTERS SYNTHESIS FROM NON-ACTIVATED KETONES IN "DRY MEDIA".

1-Hydroxyalkane phosphonic esters are readily obtained from non-activated ketones and dialkylphosphites by absorbing them together on a heterogeneous γ-alumina-potassium fluoride mixture.