91285-64-2Relevant articles and documents
Enantioselective synthesis of tarchonanthuslactone using proline-catalyzed asymmetric α-aminooxylation
George, Shyla,Sudalai, Arumugam
, p. 975 - 981 (2008/02/03)
A practical enantioselective synthesis of tarchonanthuslactone 1, an important natural product with a polyol unit, is described. The sequence of synthetic reactions involves proline-catalyzed α-aminooxylation and iodine-induced electrophilic cyclization as the chiral inducing steps.
SYNTHETIC STUDIES RELATED TO COMPACTIN AND MEVINOLIN: A NEW SYNTHESIS OF THE LACTONE SYSTEM.
Majewski, Marek,Clive, Derrick L. J.,Anderson, Paul C.
, p. 2101 - 2104 (2007/10/02)
(S)-Malic acid diethyl ester was converted into a precursor of the lactonic portion of compactin and mevinolin.The substance was coupled with benzyl p-tolyl sulfone and elaborated into the chiral lactone system of the natural products.