913650-22-3

Upstream product

• 149428-98-8 (5-chloro-2-((phenylmethyl)oxy)phenyl)acetic acid 
• 100-39-0 benzyl bromide 
• 42972-62-3 1-<5-chloro-2-(phenylmethoxy)phenyl>ethanone 
• 913650-03-0 2-(5-chloro-2-[(phenylmethyl)oxy]phenyl)acetamide 
• 1450-74-4 5-chloro-2-hydroxyacetophenone 
• 913650-10-9 2-(5-chloro-2-[(phenylmethyl)oxy]phenyl)ethanethioamide 
• 70-23-5 ethyl Bromopyruvate 

Downstream Products

• 1022905-76-5 C₁₈H₁₃ClNO₃S^(1-)*Na⁽¹⁺⁾ 
• 913652-13-8 2-({5-chloro-2-[(phenylmethyl)oxy]phenyl}methyl)-1,3-thiazole-4-carboxamide 
• 913650-39-2 ethyl 2-[(5-chloro-2-hydroxyphenyl)methyl]-1,3-thiazole-4-carboxylate 
• 913650-30-3 2-((5-chloro-2-[(phenylmethyl)oxy]phenyl)methyl)-1,3-thiazole-4-carbaldehyde 
• 913651-10-2 ethyl 2-((5-chloro-2-[(2-methylpropyl)oxy]phenyl)methyl)-1,3-thiazole-4-carboxylate 
• 913652-12-7 2-({5-chloro-2-[(phenylmethyl)oxy]phenyl}methyl)-1,3-thiazole-4-carbonitrile 
• 913652-45-6 2-({5-chloro-2-[(phenylmethyl)oxy]phenyl}methyl)-1,3-thiazole-4-amine 
• 913653-19-7 1-[2-({5-chloro-2-[(phenylmethyl)oxy]phenyl}methyl)-1,3-thiazol-4-yl]ethanone 
• 913652-23-0 methyl 2-({5-chloro-2-[(phenylmethyl)oxy]phenyl}methyl)-1,3-thiazole-4-carboximidoate 
• 913653-14-2 3-[2-({5-chloro-2-[(phenylmethyl)oxy]phenyl}methyl)-1,3-thiazol-4-yl]-1H-1,2,4-triazole 

Relevant academic research and scientific papers

Novel methylene-linked heterocyclic EP1 receptor antagonists

We describe the SAR, in terms of heterocyclic replacements, for a series of pyrazole EP1 receptor antagonists. This study led to the identification of several aromatic heterocyclic replacements for the pyrazole in the original compound. Investi

OXAZOLE AND THIAZOLE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PGE2 MEDIATED DISORDERS

Compounds of formula (I) or a pharmaceutiically acceptable derivative thereof: wherein X, Z, Y', Y'', R1 ,R2a, R2b, and Rx are as defined in the specification, a process for the preparation of such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in medicine.