913827-68-6

Basic information

• Product Name: 1,6-dihydro-1-[3-(2,3-dimethoxyphenyl)-2-propynyl]-6-oxo-2-pyridinecarbonitrile
• Synonyms: 1,6-dihydro-1-[3-(2,3-dimethoxyphenyl)-2-propynyl]-6-oxo-2-pyridinecarbonitrile
• CAS NO: 913827-68-6
• Molecular Weight: 294.31
• Mol File: 913827-68-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,6-dihydro-1-[3-(2,3-dimethoxyphenyl)-2-propynyl]-6-oxo-2-pyridinecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1,6-dihydro-1-[3-(2,3-dimethoxyphenyl)-2-propynyl]-6-oxo-2-pyridinecarbonitrile(913827-68-6)
• EPA Substance Registry System: 1,6-dihydro-1-[3-(2,3-dimethoxyphenyl)-2-propynyl]-6-oxo-2-pyridinecarbonitrile(913827-68-6)

Safety Data

• Hazardous Substances Data: 913827-68-6(Hazardous Substances Data)

Upstream product

• 25245-33-4 1-iodo-2,3-dimethoxybenzene 
• 913827-74-4 3-bromo-1-(2,3-dimethoxyphenyl)propyne 
• 89324-17-4 6-Oxo-1,6-dihydropyridine-2-carbonitrile 
• 913827-72-2 3-(2,3-dimethoxyphenyl)-2-propyn-1-ol 

Relevant articles and documents

Synthesis of the parent and substituted tetracyclic ABCD ring cores of camptothecins via 1-(3-aryl-2-propynyl)-1,6-dihydro-6-oxo-2- pyridinecarbonitriles

A new synthetic pathway to the parent and substituted ABCD ring cores of the camptothecin family of alkaloids was developed. The N-alkylation of 1,6-dihydro-6-oxo-2-pyridinecarbonitrile (2) with 3-bromo-1-phenylpropyne provided 3a using Curran's protocol.