91420-78-9

Basic information

• Product Name: (S)-((R)-oxiran-2-yl)(phenyl)methanol
• Synonyms: (S)-((R)-oxiran-2-yl)(phenyl)methanol
• CAS NO: 91420-78-9
• Molecular Weight: 150.177
• Mol File: 91420-78-9.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: (S)-((R)-oxiran-2-yl)(phenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-((R)-oxiran-2-yl)(phenyl)methanol(91420-78-9)
• EPA Substance Registry System: (S)-((R)-oxiran-2-yl)(phenyl)methanol(91420-78-9)

Safety Data

• Hazardous Substances Data: 91420-78-9(Hazardous Substances Data)

Upstream product

• 108-05-4 vinyl acetate 
• 127913-26-2 2(R*),3-epoxy-1(S*)-phenylpropan-1-ol 
• 4393-06-0 1-Phenyl-2-propen-1-ol 
• 108-86-1 bromobenzene 
• 5650-34-0 2,3-epoxy-1-phenylpropan-1-one 
• 100-52-7 benzaldehyde 
• 936210-29-6 (1S,2R)-benzoic acid 2,3-dihydroxy-1-phenyl-propyl ester 
• 98819-68-2 3-phenyl-(2R,3R)-oxiran-2-ylmethanol 
• 58210-04-1 (+)-(1S,2S)-2-(dimethylamino)-1-phenylpropane-1,3-diol 
• 31930-44-6 (Z)-1-phenyl-3-(trimethylsilyl)prop-2-en-1-ol 
• 21087-29-6 trans-3-phenylprop-2-enyl chloride 
• 31814-66-1 Phenyl-((R)-3-trimethylsilanyl-oxiranyl)-methanol 

Downstream Products

• 40421-51-0 (1R,2R)-1-phenylpropane-1,2-diol 
• 146388-55-8 (1R,2R)-2,3-epoxy-1-phenylpropan-1-ol 
• 522592-51-4 4-Methoxy-2-((S)-1-phenyl-allyloxy)-1-vinyl-benzene 
• 522592-47-8 1-((S)-1-Phenyl-allyloxy)-2-vinyl-benzene 
• 522592-41-2 (S)-2-[(R)-Phenyl-(2-vinyl-phenoxy)-methyl]-oxirane 
• 522592-45-6 (S)-2-[(R)-(5-Methoxy-2-vinyl-phenoxy)-phenyl-methyl]-oxirane 

Relevant articles and documents

Synthesis of virtually enantiopure aminodiols with three adjacent stereogenic centers by epoxidation and ring-opening

A virtually complete enantioselective synthesis of 3-amino-1,2-diols with three consecutive stereocenters was accomplished by a sequential cascade of two kinetic resolutions, which features a Sharpless or Hafnium-catalyzed asymmetric epoxidation and a subsequent W-catalyzed aminolysis. Enantiopure products with up to >99.9% ee and >99.9:0.1 dr were obtained and could serve as potential building blocks for pharmaceutical or biological significant molecules.

Highly diastereo- and enantio-selective epoxidation of secondary allylic alcohols catalyzed by styrene monooxygenase

Enantiomerically enriched glycidol derivatives with contiguous stereogenic centers were obtained in a highly diastereo- and enantio-selective epoxidation catalyzed with the styrene monooxygenase StyAB2.

Development and application of versatile bis-hydroxamic acids for catalytic asymmetric oxidation

In this article, we describe the development and preliminary results of our new designed C2-symmetric bis-hydroxamic acid (BHA) ligands and the application of the new ligands for vanadium-catalyzed asymmetric epoxidation of allylic alcohols as well as homoallylic alcohols. From this success we demonstrate the versatile nature of BHA in the molybdenum catalyzed asymmetric oxidation of unfunctionalized olefins and sulfides.