91421-24-8

Basic information

• Product Name: ethyl 2-(acetylamino)-7-oxo-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
• Synonyms: ethyl 2-(acetylamino)-7-oxo-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate;2-acetamido-7-keto-5,6-dihydro-4H-benzothiophene-3-carboxylic acid ethyl ester;2-acetamido-7-oxo-5,6-dihydro-4H-benzothiophene-3-carboxylic acid ethyl ester;AH-262/01748024;BAS 00488441;CBDivE_012034;ethyl 2-acetamido-7-oxo-5,6-dihydro-4H-1-benzothiophene-3-carboxylate;ethyl 2-acetamido-7-oxo-5,6-dihydro-4H-benzothiophene-3-carboxylate
• CAS NO: 91421-24-8
• Molecular Formula: C₁₃H₁₅NO₄S
• Molecular Weight: 281.33
• Mol File: 91421-24-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 2-(acetylamino)-7-oxo-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(acetylamino)-7-oxo-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate(91421-24-8)
• EPA Substance Registry System: ethyl 2-(acetylamino)-7-oxo-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate(91421-24-8)

Safety Data

• Hazardous Substances Data: 91421-24-8(Hazardous Substances Data)

Upstream product

• 5919-29-9 ethyl 2-acetylamino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 
• 4506-71-2 ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 

Downstream Products

• 864961-13-7 7-Oxo-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [2-(4-fluoro-2-nitro-phenyl)-ethyl]-methyl-amide 
• 864961-14-8 7-Oxo-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [2-(4-fluoro-3-nitro-Phenyl)-ethyl]-methyl-amide 
• 864961-12-6 7-oxo-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [2-(4-fluorophenyl)-ethyl]-methyl-amide 
• 128812-02-2 2-Acetylamino-7-hydroxy-6-phenylsulfanyl-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid ethyl ester 
• 128811-97-2 2-Acetylamino-7-oxo-6-phenylsulfanyl-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid ethyl ester 
• 128811-96-1 2-acetamido-6-thiocyanato-3-ethoxycarbonyl-7-oxo-4,5,6,7-tetrahydrobenzothiophene 
• 128811-94-9 3-acetamido-6-iodo-3-ethoxycarbonyl-7-oxo-4,5,6,7-tetrahydrobenzothiophene 
• 96334-46-2 7-oxo-4,5,6,7-tetrahydrobenzothiophene-3-carboxylic acid 
• 137987-66-7 2-Acetylamino-7-chloro-6-formyl-4,5-dihydro-benzo[b]thiophene-3-carboxylic acid ethyl ester 
• 113407-90-2 ethyl 2-acetylamino-6,6-dibromo-4,5,6,7-tetrahydro-7-oxobenzo[b]thiophene-3-carboxylate 
• 96334-44-0 2-amino-3-ethoxycarbonyl-7-oxo-4,5,6,7-tetrahydrobenzothiophene 

Relevant articles and documents

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Heterocyclic compound having oxime group

The present invention provides a compound that has an excellent inhibitory activity on STAT6 activation and is effective against allergic diseases, and a medicinal composition thereof. According to the present invention, disclosed is the compound represented by the General Formula (I) [where R1 and R2 independently represent a C1-6 alkyl group and the like that may have a hydrogen atom or a substituent; R3 represents a C1-6 alkyl group and the like that may have a substituent; R4 and R5 independent represents a hydrogen atom or a C1-6 alkyl group and the like that may have a substituent; R6 represents a hydrogen atom and the like; W represents —SO2— and the like; and X represents a sulphur atom and the like.]or a salt thereof, or a hydrate thereof.

SYNTHESIS AND STRUCTURE OF DERIVATIVES OF 7-OXO-4,5,6,7-TETRAHYDROBENZOTHIOPHENE AND 7-HYDROXYBENZOTHIOPHENE

The oxidation of 2-acylamino-3-ethoxycarbonyl-4,5,6,7-tetrahydrobenzothiophenes gave the corresponding 7-oxotetrahydrobenzothiophenes and some of the transformations of these compounds were studied.These compounds were used for the synthesis of 3-et