914225-72-2Relevant academic research and scientific papers
NO-RELEASING NITROOXY-CHROMENE CONJUGATES
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Paragraph 0304; 0305, (2016/12/16)
The present invention provides NO-releasing nitrooxy-alkylenyl-linked-chromene conjugates, having the structure of Formula (1) wherein R1, R2, R3, R4, X, and L are as defined in the detailed description; pharmaceutical compositions comprising at least one compound o Formula (I); and methods useful for healing wounds, preventing and treating cancer and treating actinic keratosis, cystic fibrosis, and acne, using a compound of Formula (1).
NO-RELEASING NITROOXY-CHROMENE CONJUGATES
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Paragraph 0214; 0215, (2015/08/03)
The present invention provides NO-releasing nitrooxy-alkylenyl-linked-chromene conjugates, having the structure of Formula (1 ) wherein R1, R2, R3, R4, X, and L are as defined in the detailed description; pharmaceutical compositions comprising at least one compound o Formula (I); and methods useful for healing wounds, preventing and treating cancer and treating actinic keratosis, cystic fibrosis, and acne, using a compound of Formula (1).
NO-RELEASING NONOATE(OXYGEN-BOUND)CHROMENE CONJUGATES
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Paragraph 0213; 0214, (2015/08/03)
The present invention provides NO-releasing NONOate(oxygen bound)chromene conjugates, having the structure of Formula (I): wherein Z, R1, R2, R3, R4, R5, R6, and R7 are as defined in the detailed description; pharmaceutical compositions comprising at least one compound of Formula (I); and methods useful for healing wounds, preventing and treating cancer, or treating actinic keratosis, cystic fibrosis, or acne, using a compound of Formula (I).
NO-RELEASING GUANIDINE-CHROMENE CONJUGATES
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Paragraph 0272; 0273, (2015/07/22)
The present disclosure provides NO-releasing guanidine-chromene conjugates, having the structure of Formula (I): wherein R1, R2, R3, R4, R10, and L are as defined in the detailed description; pharmaceutical compositions comprising at least one of the compounds of Formula (I); and methods useful for healing wounds, preventing and treating cancer, or treating actinic keratosis, cystic fibrosis, acne, or a disease mediated by arginine deficiency using a compound of Formula (I).
