915095-96-4Relevant articles and documents
A SYNTHESIS METHOD OF GLIFLOZIN USING CONTINUOUS PROCESS
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Paragraph 0079; 0084-0087; 0093-0107, (2020/04/21)
The present invention relates to a method for gliflozin synthesis, comprising the steps of: (a) preparing a first product by making a stream comprising an initial reactant and a lactone react with a stream comprising n-Butyllithium; and (b) making the stream comprising the first product react with a stream comprising p-toluenesulfonic acid (PTSA) to produce a second product.COPYRIGHT KIPO 2020
COMPLEX OF SGLT2 INHIBITOR AND PROCESS FOR PREPARATION THEREOF
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Page/Page column 11-12, (2017/09/08)
The present invention relates to a crystalline Form A of complex of Empagliflozin with L-Proline and process for preparation thereof. The present invention further relates to a method of preparing pure crystalline Empagliflozin via formation of the said complex.