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tert-butyl (3R,4S)-4-(2,4,5-trifluorophenyl)-1-(6-chloropyrimidin-4-yl)pyrrolidin-3-ylcarbamate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

915100-75-3

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915100-75-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 915100-75-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,5,1,0 and 0 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 915100-75:
(8*9)+(7*1)+(6*5)+(5*1)+(4*0)+(3*0)+(2*7)+(1*5)=133
133 % 10 = 3
So 915100-75-3 is a valid CAS Registry Number.

915100-75-3Relevant academic research and scientific papers

Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit

Backes, Bradley J.,Longenecker, Kenton,Hamilton, Gregory L.,Stewart, Kent,Lai, Chunqiu,Kopecka, Hana,von Geldern, Thomas W.,Madar, David J.,Pei, Zhonghua,Lubben, Thomas H.,Zinker, Bradley A.,Tian, Zhenping,Ballaron, Stephen J.,Stashko, Michael A.,Mika, Amanda K.,Beno, David W.A.,Kempf-Grote, Anita J.,Black-Schaefer, Candace,Sham, Hing L.,Trevillyan, James M.

, p. 2005 - 2012 (2008/02/01)

A novel series of pyrrolidine-constrained phenethylamines were developed as dipeptidyl peptidase IV (DPP4) inhibitors for the treatment of type 2 diabetes. The cyclohexene ring of lead-like screening hit 5 was replaced with a pyrrolidine to enable paralle

Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV)

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Page/Page column 24, (2010/11/24)

The present invention relates to compounds, which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, syndrome X, hyperinsulinemia, obesity, atherosclerosis, various immunomodulatory diseases, and other diseases.

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