915100-75-3

Basic information

• Product Name: tert-butyl (3R,4S)-4-(2,4,5-trifluorophenyl)-1-(6-chloropyrimidin-4-yl)pyrrolidin-3-ylcarbamate
• Synonyms: tert-butyl (3R,4S)-4-(2,4,5-trifluorophenyl)-1-(6-chloropyrimidin-4-yl)pyrrolidin-3-ylcarbamate
• CAS NO: 915100-75-3
• Molecular Weight: 428.842
• Mol File: 915100-75-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl (3R,4S)-4-(2,4,5-trifluorophenyl)-1-(6-chloropyrimidin-4-yl)pyrrolidin-3-ylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (3R,4S)-4-(2,4,5-trifluorophenyl)-1-(6-chloropyrimidin-4-yl)pyrrolidin-3-ylcarbamate(915100-75-3)
• EPA Substance Registry System: tert-butyl (3R,4S)-4-(2,4,5-trifluorophenyl)-1-(6-chloropyrimidin-4-yl)pyrrolidin-3-ylcarbamate(915100-75-3)

Safety Data

• Hazardous Substances Data: 915100-75-3(Hazardous Substances Data)

Upstream product

• 915100-74-2 tert-butyl (3R,4S)-1-benzyl-4-(2,4,5-trifluorophenyl)pyrrolidin-3-ylcarbamate 
• 1193-21-1 4,6-dichloropyrimidine 
• 936251-05-7 C₁₇H₁₅F₃N₂O₂ 
• 915100-66-2 (E)-1,2,4-trifluoro-5-(2-nitrovinyl)benzene 
• 915100-83-3 [(3R,4S)-4-(2,4,5-trifluorophenyl)pyrrolidin-3-yl]carbamic acid tert-butyl ester 

Downstream Products

• 915100-76-4 (3R,4S)-1-(6-thien-3-ylpyrimidin-4-yl)-4-(2,4,5-trifluorophenyl)pyrrolidin-3-amine 

Relevant articles and documents

Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit

A novel series of pyrrolidine-constrained phenethylamines were developed as dipeptidyl peptidase IV (DPP4) inhibitors for the treatment of type 2 diabetes. The cyclohexene ring of lead-like screening hit 5 was replaced with a pyrrolidine to enable paralle