915140-06-6 Usage
Description
4-Pyridinecarboxylic acid, 2-(hydroxymethyl)-, commonly known as Hydroxymethyl nicotinic acid, is a chemical compound that belongs to the pyridine and pyridine derivatives class. It features a carboxylic acid and hydroxyl group attached to a methyl group in its structure, making it a relatively stable compound. This versatile chemical is particularly useful in the field of chemistry, especially in medicinal or pharmaceutical applications, due to its involvement in various biological activities. Its properties can be tailored when combined with other chemicals to produce specific therapeutic effects. However, adequate precautions should be taken while handling this chemical due to its potential hazards.
Uses
Used in Pharmaceutical Industry:
4-Pyridinecarboxylic acid, 2-(hydroxymethyl)is used as a pharmaceutical intermediate for the synthesis of various drugs and medications. Its unique structure and properties allow it to be manipulated and combined with other chemicals to produce specific therapeutic effects, making it a valuable component in the development of new medications.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 4-Pyridinecarboxylic acid, 2-(hydroxymethyl)is used as a key building block for the design and synthesis of novel compounds with potential biological activities. Its versatile structure enables researchers to explore its interactions with various biological targets, leading to the discovery of new drugs and therapeutic agents.
Used in Chemical Synthesis:
4-Pyridinecarboxylic acid, 2-(hydroxymethyl)is utilized as a starting material or intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its reactivity and functional groups make it a suitable candidate for various chemical reactions, facilitating the production of a wide range of products.
Used in Analytical Chemistry:
4-PYRIDINECARBOXYLIC ACID, 2-(HYDROXYMETHYL)can also be employed as a reference material or standard in analytical chemistry for the development and validation of analytical methods, such as high-performance liquid chromatography (HPLC), gas chromatography (GC), and mass spectrometry (MS). Its well-defined structure and properties make it an ideal candidate for assessing the performance of these analytical techniques.
Check Digit Verification of cas no
The CAS Registry Mumber 915140-06-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,5,1,4 and 0 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 915140-06:
(8*9)+(7*1)+(6*5)+(5*1)+(4*4)+(3*0)+(2*0)+(1*6)=136
136 % 10 = 6
So 915140-06-6 is a valid CAS Registry Number.
915140-06-6Relevant articles and documents
Zinc and Cadmium Complexes of Pyridinemethanol Carboxylates: Metal Carboxylate Zwitterions and Metal–Organic Frameworks
Lin, Shi-Xin,Liu, Quan,Liu, Yan,Niu, Ru-Jie,Young, David J.,Zhang, Wen-Hua
, p. 832 - 837 (2020/06/03)
The heterofunctional lactone furo[3,4-b]pyridin-5(7H)-one (L1) undergoes a coordination-induced ring-opening reaction with Zn(NO3)2 ? 6H2O to yield the zwitterionic [Zn(L1′)2(H2O)2] (1, L1′=2-(hydroxymethyl)nicotinate) with an uncoordinated carboxylate. The same reaction with Cd(NO3)2 ? 4H2O provides a two-dimensional (2D) network of [Cd(L1′)2]n (3) with the carboxylates coordinated to cadmium(II) propagating the assembly. The corresponding reactions of Zn(NO3)2 ? 6H2O and Cd(NO3)2 ? 4H2O with 2-(hydroxymethyl)isonicotinic acid (HL2) generated zwitterionic [Zn(L2)2(H2O)2] (2) and a 2D network [Cd(L2)2]n?nDMF (4, DMF=N,N′-dimethylformamide), respectively. Complexes 1–4 are weakly emissive, giving ligand-centered emissions at 409 nm (1), 412/436 nm (2), 404 nm (3), and 412/436 nm (4) in CHCl3 solutions upon excitation at 330 nm. This work points to the potential of using ‘hidden’ functionalities widely found in small organic molecules and natural products for the construction of coordination complexes with new functionality and potential applications.
Isolation of first row transition metal-carboxylate zwitterions
Armaghan, Mahsa,Lu, W. Y. James,Wu, Di,Wei, Yao,Yuan, Feng-Ling,Ng, Seik Weng,Amini, Mostafa M.,Zhang, Wen-Hua,Young, David J.,Hor, T. S. Andy,Lang, Jian-Ping
, p. 42978 - 42989 (2015/05/27)
Zwitterionic 3d metal carboxylates of Zn(ii), Cu(ii), Ni(ii) and Co(ii) have been isolated and structurally authenticated by X-ray crystallography. A series of 2-hydroxymethylpyridine-carboxylate ligands with different sizes and shapes demonstrate variabl
