91526-17-9

Basic information

• Product Name: 4-forMyloxyMethyl-5-Methyl- 1,3-dioxolene-2-one
• Synonyms: 4-[(formyloxy)methyl]-5-methyl-1,3-Dioxol-2-one;4-forMyloxyMethyl-5-Methyl- 1,3-dioxolene-2-one
• CAS NO: 91526-17-9
• Molecular Formula: C₆H₆O₅
• Molecular Weight: 158.10884
• Mol File: 91526-17-9.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-forMyloxyMethyl-5-Methyl- 1,3-dioxolene-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-forMyloxyMethyl-5-Methyl- 1,3-dioxolene-2-one(91526-17-9)
• EPA Substance Registry System: 4-forMyloxyMethyl-5-Methyl- 1,3-dioxolene-2-one(91526-17-9)

Safety Data

• Hazardous Substances Data: 91526-17-9(Hazardous Substances Data)

Upstream product

• 80841-78-7 4-chloromethyl-5-methyl-1,3-dioxol-2-one 
• 37830-90-3 4,5-Dimethyl-1,3-dioxole-2-one 
• 80715-25-9 4-bromomethyl-2-oxo-1,3-dioxolene 
• 64-18-6 formic acid 
• 80715-22-6 4-bromomethyl-1,3-dioxa-5-methylcyclopentene-2-one 

Downstream Products

• 91526-18-0 4-hydroxymethyl-5-methyl-[1,3]dioxol-2-one 

Relevant articles and documents

On the preparation of 4-hydroxymethyl-5-methyl-1,3-dioxol-2-one

A practical and efficient conversion of 4-bromomethyl-5-methyl-1,3-dioxol-2-one 1 into the corresponding carbinol 2, a useful building block for the preparation of prodrugs, is reported.

N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE

The present invention provides a compound of formula (I): wherein R1a is optionally substituted C1-6 alkyl, etc.; R1m is hydrogen atom, etc.; G1, G2, G3 and G4 are (i), etc. ((i) G1 is -N(R1b)-, G2 is -CO-, G3 is -C(R1c)(R1d)-, and G4 is oxygen, etc.); R1b is optionally substituted C1-6 alkyl, etc.; R1c and R1d are each independently optionally substituted C1-6 alkyl, etc.; R2 is optionally substituted C1-6 alkyl, etc.; R3a, R3b, R3c, and R3d are each independently a group: -A-B (A is a single bond, etc., B is hydrogen atom, etc.), etc.; n is 1, etc.; R5 is C1-4 alkoxycarbonyl, etc., or a pharmaceutically acceptable salt thereof, which is useful as a renin inhibitor.

Dioxolenylmethyl carbamates pro moieties for amine drugs

This invention relates to a the use of new oxodioxolenylmethyl carbamates to produce bioreversible neutral prodrugs from primary and secondary amines.