91547-59-0

Basic information

• Product Name: 1,2-DIDEOXY-D-RIBOSE
• Synonyms: 1,4-ANHYDRO-D-ERYTHRO-PENTITOL;1,2-DIDEOXY-D-RIBOSE;1,2-Dideoxy-D-ribofuranose;1,2-dideoxyribofuranose;1,4-Anhydro-2-deoxy-D-erythro-pentitol;1,4-Anhydro-2-deoxy-D-ribitol;(2R,3S)-2-(Hydroxymethyl)tetrahydrofuran-3-ol;1,2-Dideoxy-D-ribose (1,4-anhydro-D-erythro-pentitol)
• CAS NO: 91547-59-0
• Molecular Formula: C₅H₁₀O₃
• Molecular Weight: 118.13
• Mol File: 91547-59-0.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 275.1°Cat760mmHg
• Flash Point: 120.2°C
• Appearance: /
• Density: 1.239g/cm³
• Vapor Pressure: 0.000657mmHg at 25°C
• Refractive Index: 1.496
• PKA: 14.25±0.40(Predicted)
• CAS DataBase Reference: 1,2-DIDEOXY-D-RIBOSE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-DIDEOXY-D-RIBOSE(91547-59-0)
• EPA Substance Registry System: 1,2-DIDEOXY-D-RIBOSE(91547-59-0)

Safety Data

• Hazardous Substances Data: 91547-59-0(Hazardous Substances Data)

Usage

Uses

1,4-Anhydro-2-deoxy-D-erythro-pentitol was used as a reactant in the study of simple fluorescent pyrimidine analogs that detect the presence of abasic sites in DNA.

InChI:InChI=1/C5H10O3/c6-3-5-4(7)1-2-8-5/h4-7H,1-3H2/t4-,5+/m0/s1

Upstream product

• 51255-17-5 1-O-methyl-2-deoxy-D-ribofuranoside 
• 50-89-5 thymidine 
• 4330-34-1 methyl 3,5-di-O-toluoyl-2-deoxy-D-ribofuranose 
• 151589-07-0 5-(hydroxymethyl)-2,3-dihydrofuran 
• 57445-90-6 pent-4-ene-1,3-diol 
• 401813-15-8 (2S,3S)-2-(tert-butyldiphenylsilanyloxymethyl)tetrahydrofuran-3-ol 
• 127761-83-5 1,4-anhydro-5-O-(tert-butyldiphenylsilyl)-2-deoxy-D-erythro-pent-1-enitol 
• 127791-68-8 1,4-anhydro-5-O-(tert-butyldiphenylsilyl)-2-deoxy-3-O-(trimethylsilyl)-D-erythro-pent-1-enitol 
• 4330-21-6 2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride 
• 452-51-7 D-2-deoxyribose 
• 100269-88-3 di-O-toluoyl-1,2-dideoxy-D-ribose 
• 3601-89-6 Hoffer's chlorosugar 
• 13942-76-2 2-Deoxy-D-ribitol 

Downstream Products

• 151265-78-0 (2R,3S)-2-[(4-Methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-ol 
• 178977-73-6 2,2,2-Trifluoro-N-{3-[((2R,3S)-3-hydroxy-tetrahydro-furan-2-ylmethoxy)-diphenyl-methyl]-benzyl}-acetamide 
• 1332834-93-1 5-O-benzoyl-1,2-dideoxy-D-ribose 
• 1332834-94-2 5-O-toluoyl-1,2-dideoxy-D-ribose 
• 1332834-95-3 5-O-p-methoxybenzoyl-1,2-dideoxy-D-ribose 
• 1332834-96-4 5-O-p-nitrobenzoyl-1,2-dideoxy-D-ribose 
• 1332834-97-5 5-O-p-fluorobenzoyl-1,2-dideoxy-D-ribose 
• 51255-17-5 1-O-methyl-2-deoxy-D-ribofuranoside 
• 191982-97-5 [(2R,3S)-3-hydroxytetrahydrofuran-2-yl]methyl 4-methylbenzenesulfonate 
• 95049-01-7 5-O-(4,4'-dimethoxytriphenylmethyl)-1,4-anhydro-2-deoxy-D-ribitol 
• 145350-21-6 Benzoic acid (2R,3S,5R)-3-hydroxy-3-methyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester 

Relevant articles and documents

Practical and Reliable Synthesis of 1,2-Dideoxy-D-ribofuranose and its Application in RNAi Studies

We developed a practical and reliable method for synthesizing an abasic deoxyribonucleoside, 1,2-dideoxy-D-ribofuranose (dRH) via elimination of nucleobase from thymidine. To synthesize oligonucleotides bearing dRH by the standard ph

An expedient biocatalytic procedure for abasic site precursors useful in oligonucleotide synthesis

Preparation of abasic site precursors through a divergent chemoenzymatic synthesis has been accomplished. Several biocatalysts and acylating agents were studied furnishing a practical and scalable green method useful for industrial applications. Highly re

COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS

Disclosed herein are compounds of formula (I) wherein Ring A and R1 are as defined in the specification. Pharmaceutical compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and pharmaceutical compositions are also disclosed.