95049-01-7

Upstream product

• 1332834-98-6 5-O-(4,4'-dimethoxytrityl)-3-O-toluoyl-1,2-dideoxy-D-ribose 
• 1332834-92-0 3-O-toluoyl-1,2-dideoxy-D-ribose 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 100269-88-3 di-O-toluoyl-1,2-dideoxy-D-ribose 
• 127791-68-8 1,4-anhydro-5-O-(tert-butyldiphenylsilyl)-2-deoxy-3-O-(trimethylsilyl)-D-erythro-pent-1-enitol 
• 127761-83-5 1,4-anhydro-5-O-(tert-butyldiphenylsilyl)-2-deoxy-D-erythro-pent-1-enitol 
• 401813-15-8 (2S,3S)-2-(tert-butyldiphenylsilanyloxymethyl)tetrahydrofuran-3-ol 
• 91547-59-0 (2R,3S)-2-(hydroxymethyl)tetrahydrofuran-3-ol 

Downstream Products

• 1217414-14-6 (2R,3S)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-methoxytetrahydrofuran 
• 180979-33-3 triethylammonium-[1,2-dideoxy-5-O-(4,4'-dimethoxytrityl)-D-ribofuranose-3-O-hydrogenphosphonate] 
• 552859-22-0 (2R,3R)-2-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-ol 

Relevant academic research and scientific papers

Practical and Reliable Synthesis of 1,2-Dideoxy-D-ribofuranose and its Application in RNAi Studies

We developed a practical and reliable method for synthesizing an abasic deoxyribonucleoside, 1,2-dideoxy-D-ribofuranose (dRH) via elimination of nucleobase from thymidine. To synthesize oligonucleotides bearing dRH by the standard ph

An expedient biocatalytic procedure for abasic site precursors useful in oligonucleotide synthesis

Preparation of abasic site precursors through a divergent chemoenzymatic synthesis has been accomplished. Several biocatalysts and acylating agents were studied furnishing a practical and scalable green method useful for industrial applications. Highly re

NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS

Disclosed herein are cannabinoid receptor ligands of formula (I) wherein A1, A5, Rx, X4, and z are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS

Disclosed herein are compounds of formula (I) wherein Ring A and R1 are as defined in the specification. Pharmaceutical compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and pharmaceutical compositions are also disclosed.

NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS

The present invention relates compounds of formula (I) wherein A and R1 are as defined in the specification, pharmaceutical compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and pharmaceutical compositions.

Oligophosphates with an antiviral action

Novel oligophosphates with an antiviral action of the formula STR1 in which n is 3-50, B and E are, independently of one another, O, S or NH, A is O, NR or S, D is O, S or NR2, in which independently each R is H, alkyl, aralkyl or aryl, and