127761-83-5

Basic information

• Product Name: 1,4-anhydro-5-O-(tert-butyldiphenylsilyl)-2-deoxy-D-erythro-pent-1-enitol
• Synonyms: 1,4-anhydro-5-O-(tert-butyldiphenylsilyl)-2-deoxy-D-erythro-pent-1-enitol
• CAS NO: 127761-83-5
• Molecular Weight: 354.521
• Mol File: 127761-83-5.mol

Chemical Properties

• CAS DataBase Reference: 1,4-anhydro-5-O-(tert-butyldiphenylsilyl)-2-deoxy-D-erythro-pent-1-enitol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-anhydro-5-O-(tert-butyldiphenylsilyl)-2-deoxy-D-erythro-pent-1-enitol(127761-83-5)
• EPA Substance Registry System: 1,4-anhydro-5-O-(tert-butyldiphenylsilyl)-2-deoxy-D-erythro-pent-1-enitol(127761-83-5)

Safety Data

• Hazardous Substances Data: 127761-83-5(Hazardous Substances Data)

Upstream product

• 127791-68-8 1,4-anhydro-5-O-(tert-butyldiphenylsilyl)-2-deoxy-3-O-(trimethylsilyl)-D-erythro-pent-1-enitol 
• 101527-40-6 5'-O-tert-butyldiphenylsilylthymidine 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 50-89-5 thymidine 

Downstream Products

• 91547-59-0 (2R,3S)-2-(hydroxymethyl)tetrahydrofuran-3-ol 
• 95049-01-7 5-O-(4,4'-dimethoxytriphenylmethyl)-1,4-anhydro-2-deoxy-D-ribitol 
• 544687-59-4 (1S,5R)-1-(tert-butyldiphenylsilanyloxymethyl)-7-methyl-2,6,8-trioxaspiro[4.5]decane 
• 544687-58-3 (2S,3R)-2-(tert-butyldiphenylsilanyloxymethyl)-3-(2'-hydroxyethyl)tetrahydrofuran-3-ol 
• 544687-57-2 (2S,3S)-2-(tert-butyldiphenylsilanyloxymethyl)-3-vinyltetrahydrofuran-3-ol 
• 544687-56-1 (2S)-2-(tert-butyldiphenylsilanyloxymethyl)-4,5-dihydro-2H-furan-3-one 
• 544687-62-9 (1S,5R)-1-(tosyloxymethyl)-7-methyl-2,6,8-trioxaspiro[4.5]decane 
• 263764-83-6 buergerinin G 
• 401813-15-8 (2S,3S)-2-(tert-butyldiphenylsilanyloxymethyl)tetrahydrofuran-3-ol 
• 127761-87-9 (3R,4R)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-2,6-dioxa-bicyclo[3.1.0]hexan-4-ol 

Relevant articles and documents

Synthesis of a New Furanoid Glycal Auxiliary

A route is investigated for the synthesis of 3-O-allyl-1,4-anhydro-5-O- tert-butyldiphenylsilyl-2-deoxy-D-erythro-pent-1-enitol. The highest overall yield was obtained when 5′-O-(tert-butyldiphenylsilyl)thymidine was converted to the corresponding furanoi

Practical and Reliable Synthesis of 1,2-Dideoxy-D-ribofuranose and its Application in RNAi Studies

We developed a practical and reliable method for synthesizing an abasic deoxyribonucleoside, 1,2-dideoxy-D-ribofuranose (dRH) via elimination of nucleobase from thymidine. To synthesize oligonucleotides bearing dRH by the standard ph

One-pot synthesis of β-N-glycosyl imidazole analogues via a palladium-catalysed decarboxylative allylation

A concise and highly efficient strategy for the synthesis of N-glycosyl imidazole analogues is reported. This reaction is based on a palladium catalysed decarboxylative allylation and three steps, namely, carbamation, decarboxylation and allylation are involved. All the substrates can afford the desired products with excellent yields and selectivities. the Partner Organisations 2014.

Facile preparation of protected furanoid glycals from thymidine

The synthesis of O-silyl- and O-acyl-protected furanose glycals from free thymidine was investigated. The method of glycal formation reported by Pedersen et al. was successfully expanded to include 5-ester (toluoyl) protected glycals as well as various combinations of 5'-ester and 3- and 5- tert-butyldimethylsilyl and tert-butyldiphenylsilyl protection. Gram quantities of furanoid glycals can be prepared in a few days in two-four steps in overall yields ranging from 17 to 80%.