916080-55-2

Upstream product

• 22744-12-3 [4-(methoxycarbonyl)phenyl]acetic acid 
• 22744-13-4 4-(2-diazoacetyl)benzoic acid methyl ester 
• 7377-26-6 4-Methoxycarbonylbenzoyl chloride 
• 142667-04-7 4-chlorocarbonylmethyl-benzoic acid methyl ester 
• 22744-49-6 4-(3-Diazo-2-oxo-propyl)-benzoic acid methyl ester 
• 1679-64-7 Monomethyl terephthalate 
• 916080-53-0 methyl 4-(3-chloro-2-oxopropyl)benzoate 
• 100643-27-4 2,6-diamino-3H-pyrimidin-4-one 

Downstream Products

• 916080-57-4 4-[(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)methyl]benzoic acid 
• 518063-74-6 C₁₉H₁₉N₅O₆ 
• 916080-59-6 diethyl N-{4-[(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)methyl]benzoyl}-L-glutamate 

Relevant academic research and scientific papers

Synthesis and evaluation of a classical 2,4-diamino-5-substituted-furo[2,3-d]pyrimidine and a 2-amino-4-oxo-6-substituted-pyrrolo[2,3-d]pyrimidine as antifolates

Two classical antifolates, a 2,4-diamino-5-substituted furo[2,3-d]pyrimidine and a 2-amino-4-oxo-6-substituted pyrrolo[2,3-d]pyrimidine, were synthesized as potential inhibitors of dihydrofolate reductase (DHFR) and thymidylate synthase (TS). The synthese