91653-14-4

Upstream product

• 32588-36-6 indolylacetic acid 

Downstream Products

• 1618136-59-6 C₂₇H₃₂N₃O₅⁽¹⁺⁾*C₇H₇O₃S^(1-) 
• 1618136-57-4 C₂₈H₃₀N₃O₃⁽¹⁺⁾*C₇H₇O₃S^(1-) 
• 1618136-55-2 C₂₄H₂₆N₃O₄⁽¹⁺⁾*C₇H₇O₃S^(1-) 
• 1618136-53-0 C₃₀H₂₆N₃O₅⁽¹⁺⁾*C₇H₇O₃S^(1-) 
• 77251-57-1 11-methyl-6H-pyrido<4,3-b>carbazole-5-carbaldehyde 
• 108320-76-9 2-(p-nitrobenzyl)-5-carbomethoxy-11-methyl-6H-pyrido<4,3-b>carbazolium bromide 
• 108320-78-1 5-(hydroxymethyl)-11-methyl-6H-pyrido<4,3-b>carbazole 
• 108320-73-6 3-[1-(2-Methoxycarbonylmethyl-1H-indol-3-yl)-vinyl]-1-(4-nitro-benzyl)-pyridinium; bromide 
• 108320-72-5 1-Benzyl-3-[1-(2-methoxycarbonylmethyl-1H-indol-3-yl)-vinyl]-pyridinium; bromide 
• 108320-75-8 2-Benzyl-5-methoxycarbonyl-11-methyl-6H-pyrido[4,3-b]carbazol-2-ium; bromide 
• 110527-58-7 2-(4-Dimethylamino-phenylamino)-11-methyl-2H-pyrido[4,3-b]carbazole-5-carboxylic acid methyl ester 
• 110547-49-4 2-(4-Amino-benzyl)-11-methyl-2,3,4,6-tetrahydro-1H-pyrido[4,3-b]carbazole-5-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis and in vitro antitumor activity of novel 2-alkyl-5- methoxycarbonyl-11-methyl-6H-pyrido[4,3-b]carbazol-2-ium and 2-alkylellipticin-2-ium chloride derivatives

Twenty-one types of novel ellipticine derivatives and pyridocarbazoles (5-methoxycarbonyl-11-methyl-6H-pyrido[4,3-b]carbazoles) with a nitrosourea moiety, linked by an oxydiethylene unit at the 2 position, were synthesized, and their cytotoxicity against HeLa S-3 cells was evaluated. Some of these new compounds exhibited potent antitumor activity by comparison with that of ellipticine.

SYNTHESIS OF ELLIPTICINE

The 6H-pyridocarbazole system is efficiently synthesized by intramolecular attack of an ester enolate on an unactivated pyridinium salt.