91671-15-7Relevant academic research and scientific papers
A simple route to 1,4-addition reactions by Co-catalyzed reductive coupling of organic tosylates and triflates with activated alkenes
Hsieh, Jen-Chieh,Chu, Yi-Hua,Muralirajan, Krishnamoorthy,Cheng, Chien-Hong
, p. 11584 - 11587 (2017/10/27)
An efficient Co-catalyzed 1,4-addition reaction of alkyl/aryl triflates and tosylates with activated alkenes is described. In this reaction, an air-stable cobalt(ii) complex, a mild reducing agent Zn and a simple proton source (H2O) are used. A radical mechanism for the addition of alkyl tosylates to activated alkenes is likely involved.
NOVEL COMPOUNDS
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Page/Page column 62-63, (2012/03/26)
Disclosed are retinoid-related orphan receptor gamma (RORγ) modulators and their use in the treatment of diseases mediated by RORγ.
Direct synthesis of ester-containing indium homoenolate and its application in palladium-catalyzed cross-coupling with aryl halide
Shen, Zhi-Liang,Goh, Kelvin Kau Kiat,Wong, Colin Hong An,Yang, Yong-Sheng,Lai, Yin-Chang,Cheong, Hao-Lun,Loh, Teck-Peng
supporting information; experimental part, p. 4778 - 4780 (2011/05/15)
An efficient method for the synthesis of ester-containing indium homoenolate via a direct insertion of indium into β-halo ester in the presence of CuI/LiCl was described. The synthetic utility of the indium homoenolate was demonstrated by palladium-cataly
Palladium-catalyzed heck coupling-hydrogenation: Highly efficient one-pot synthesis of dibenzyls and alkyl phenyl esters
Kantam, M. Lakshmi,Chakravarti, Rajashree,Chintareddy, Venkat Reddy,Sreedhar,Bhargava, Suresh
supporting information; experimental part, p. 2544 - 2550 (2009/08/14)
An efficient method for the synthesis of industrially important dibenzyls and alkyl phenyl esters via sequential Heck coupling and hydrogenation of the alkenyl double bond in one pot with a single recyclable catalyst under mild conditions has been realised. The catalyst was recovered by simple filteration and reused for several cycles with consistent activity.
Addition of electrochemically prepared arylzinc species onto activated olefins via a cobalt catalysis
Gomes, Paulo,Gosmini, Corinne,Périchon, Jacques
, p. 1673 - 1676 (2007/10/03)
The consumable anode process allows the electrochemical preparation of arylzinc compounds in the presence of cobalt chloride as catalyst in a mixed solvent acetonitrile/pyridine (9:1). Conjugate addition of these organometallic reagents to olefins is also obtained in good yields via a new method using CoBr2(2,2′-bipyridine)2 as catalyst.
Palladium-Catalyzed Cross-Coupling Reaction of Alkyltrifluorosilanes with Aryl Halides
Matsuhashi, Hayao,Asai, Satoshi,Hirabayashi, Kazunori,Hatanaka, Yasuo,Mori, Atsunori,Hiyama, Tamejiro
, p. 437 - 444 (2007/10/03)
A cross-coupling reaction of alkyltrifluorosilanes with aryl halides was achieved using a catalytic amount of tetrakis-(triphenylphosphine)palladium(0) and excess of tetrabutylammonium fluoride (TBAF) at 100°C with high chemoselectitvity. Functional groups like nitro, ketone carbonyl, and formyl tolerated the coupling conditions. Because potassium(18-crown-6) alkyltetrafluorosilicates also underwent a cross-coupling reaction in the presence of an additional molar amount of TBAF, the active species of the coupling reaction was assumed to be pentacoordinate silicates. TBAF in excess was considered to be required for trapping the tetrafluorosilane produced in the catalytic cycle of the cross-coupling reaction.
Palladium catalyzed cross-coupling reaction of functionalized alkyltrifluorosilanes with aryl halides
Matsuhashi, Hayao,Kuroboshi, Manabu,Hatanaka, Yasuo,Hiyama, Tamejiro
, p. 6507 - 6510 (2007/10/02)
A variety of alkyltrifluorosilanes were found to couple with aryl halides in the presence of Pd(PPh3)4 catalyst and tetrabutylammonium fluoride (TBAF) to give the corresponding cross-coupled products in moderate to good yields.
