916976-33-5

Upstream product

• 922504-26-5 phenyl(1-tosylpiperidin-4-yl)methanone 
• 1127547-60-7 C₂₅H₂₇NO₃S 
• 1342798-41-7 C₂₅H₂₇NO₃S 
• 124-63-0 methanesulfonyl chloride 
• 922504-30-1 1-(4-methylphenylsulfonyl)-5,5-diphenylazepan-4-one 
• 582299-09-0 {1-[(4-methylphenyl)sulfonyl]piperidin-4-yl}methanol 
• 553666-09-4 1-[(4-methylphenyl)sulfonyl]piperidine-4-carbaldehyde 
• 1126-09-6 4-carbethoxypiperidine 
• 297180-07-5 4-ethoxycarbonyl-1-(4-methylphenylsulfonyl)piperidine 
• 98-59-9 p-toluenesulfonyl chloride 
• 37586-22-4 4-benzoylpiperidine 
• 852860-46-9 diphenyl[1-(toluene-4-sulfonyl)piperidin-4-yl]methanol 

Downstream Products

• 922504-30-1 1-(4-methylphenylsulfonyl)-5,5-diphenylazepan-4-one 
• 22940-59-6 4-benzoyl-4-phenyl-1-(p-toluenesulfonyl)piperidine 
• 1257268-69-1 C₂₅H₂₆FNO₃S 
• 1342798-41-7 C₂₅H₂₇NO₃S 
• 1342798-49-5 C₂₅H₂₅NO₂S 
• 1342798-50-8 C₂₅H₂₇NO₂S 
• 1342798-42-8 C₂₆H₂₉NO₅S₂ 

Relevant academic research and scientific papers

Synthesis of cis-4,5-diarylazepanes

Substituted cis-4,5-diarylazepanes are synthesized in modest overall yields starting from 5,5-diarylazepan-4-ones by areduction, mesylation, rearrangement, and hydrogenation reaction sequence. Georg Thieme Verlag Stuttgart New York.

BF3-OEt2-mediated rearrangement of (4-phenylpiperidin-4-yl)-arylmethanols

Synthesis of several 4-benzhydrylidenepiperidine analogs has been established starting from different (4-phenylpiperidin-4-yl)-arylmethanols via boron trifluoride etherate mediated rearrangement. The possible rearranged mechanism was proposed. Boron trifluoride etherate-mediated rearrangement of the related derivatives was also examined. It presents a novel rearrangement reaction catalyzed by boron trifluoride etherate and broadens the scope of application.

Synthesis of diarylazepan-4-ones

Synthesis of several 3,3-diarylazepan-4-ones and 5,5-diarylazepan-4-ones has been established starting from two tetrasubstituted olefins, which is derived from commercially available piperidine-3-carboxylic acid ethyl ester and piperidine-4-carboxylic aci

CAN-mediated rearrangement of 4-benzhydrylidenepiperidines

Several 1-substituted phenyl-(4-phenylpiperidin-4-yl)methanones are synthesized in modest overall yields starting from the reaction of different 1-substituted 4-benzhydrylidenepiperidines via CAN-mediated rearrangement. This facile strategy was also used to synthesize meperidine analog.